Alnylam Pharmaceuticals · 1 day ago
Scientist, Biology
Alnylam Pharmaceuticals is a leader in RNAi therapeutics, seeking a Scientist in Biology to contribute to targeted delivery efforts for expanding RNAi into new tissues. This lab-based role involves designing plasmid constructs, establishing tools for evaluating delivery strategies, and collaborating with various teams to optimize RNA drugs for tissue-specific delivery.
Responsibilities
Design plasmid contructs for generating cell lines stably expressing membrane proteins
Organize and maintain a functional inventory of plasmid sequences
Establish tools, execute assays, and develop in vitro models to evaluate delivery and activity of siRNA conjugates
Work collaboratively across the organization to optimize RNA drugs for tissue-specific delivery
Design controlled experiments, analyze data, and present findings to various groups across the research organization
Qualification
Required
PhD in biochemistry, molecular biology, or a related field with up to 3 years of work experience in an industry setting
Experience in the design and optimization of plasmids for efficient cellular expression of membrane proteins is required
Expertise with mammalian cell culture including general maintenance, transfection and transduction, imaging techniques, and cell line generation is required
Strong interpersonal skills and excellent communication skills (written and oral) are required
Preferred
Experience with standard biochemical and cell-based assays for assessing receptor/ligand interactions (flow cytometry, microscopy, ELISA, BLI) is strongly preferred
Experience with plasmid registration and inventory maintenance is preferred
Benefits
Comprehensive benefits including medical, dental, and vision coverage
Life and disability insurance
A lifestyle reimbursement program
Flexible spending and health savings accounts
A 401(k) with a generous company match
Paid time off
Wellness days
Holidays
Two company-wide recharge breaks
Generous family resources and leave
Company
Alnylam Pharmaceuticals
Alnylam Pharmaceuticals is a biopharmaceutical company focused on the discovery, development and commercialization.
H1B Sponsorship
Alnylam Pharmaceuticals has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2022 (18)
2021 (19)
2020 (7)
Funding
Current Stage
Public CompanyTotal Funding
$4.55BKey Investors
Blackstone Life SciencesBlackstone CreditRegeneron
2025-09-09Post Ipo Debt· $661.25M
2022-09-12Post Ipo Debt· $900M
2022-03-04IPO
Recent News
2025-12-22
2025-12-20
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