Apply on Employer Site

4D Molecular Therapeutics · 1 month ago

Executive Medical Director

Emeryville, California

Full-time

Onsite

Director/Executive

$352K/yr - $422K/yr

9+ years exp

4DMT is a leading late-stage biotechnology company focused on advancing durable and disease-targeted therapeutics. The Executive Medical Director will oversee the design, execution, and analysis of clinical trials in the Ophthalmology Therapeutic Area, providing clinical leadership and ensuring the delivery of study protocols and conduct.

BiotechnologyGenetics

Growth Opportunities

Responsibilities

Provides clinical leadership to multidisciplinary study execution teams drawn from clinical operations, clinical science, biometrics, regulatory affairs, CMC, pharm/tox, drug safety, commercial, and alliance partners

Has lead accountability on the study teams for delivery of study protocols, study conduct, and study readouts

Organizes and leads scientific advisory board meetings. Interacts with external experts and stakeholders to gather input

Serves as medical monitor on clinical studies

Serves as the primary clinical author of development plans, study protocols, amendments, ICFs, IBs, INDs, annual reports, CSRs, regulatory submissions / correspondence, and project-related documents. Accountable for the accuracy of all medical content of such documents

Works with the research organization and the portfolio management team to identify and support new project opportunities

Collaborates to identify program risks, and to create and implement mitigation strategies

Other duties as assigned

Qualification

Medical Degree (M.D.)Ophthalmology residencyClinical ophthalmology researchPhase 3 clinical trialsGene therapy studiesNDA/BLA/MAA submissionsData analysisICH-GCP knowledgeFDA regulatory guidelinesPublic speakingEffective communication

Required

Medical Degree (M.D.)

Residency training in Ophthalmology with a preference for subspecialty training in retina

9+ years of clinical ophthalmology research in the biopharmaceutical industry

Experience with medical monitoring and oversight of Phase 3 retina clinical trials

Experience with gene therapy clinical studies

Experience in other phases (Phase 1, 2, 4) of clinical research

Experience with NDA/BLA/MAA submission planning and execution

Experience in data analysis, data interpretation, and medical writing

Knowledge of ICH-GCP and FDA regulatory guidelines

Knowledge of international regulatory guidelines

Effective written and verbal communication skills, including public speaking

Preferred

Board certification/retina fellowship training are a plus

Company

4D Molecular Therapeutics

4D Molecular Therapeutics designs, develops, and commercializes transformative gene therapeutic products for unmet medical conditions.

Founded in 2013

Emeryville, California, USA

51-200 employees

http://www.4dmoleculartherapeutics.com

Funding

Current Stage

Public Company

Total Funding

$702.5M

Key Investors

Cystic Fibrosis FoundationViking Global Investors

2025-11-06Post Ipo Equity· $100M

2025-10-13Post Ipo Equity· $7.5M

2024-02-06Post Ipo Equity· $300M

Leadership Team

David Kirn

Co-Founder & CEO

Liansheng Zhu

Sr VP Biometrics and Data Quality

Recent News

GlobeNewswire

4DMT Provides Company Update and Anticipated Development Milestones for 2026

2026-01-07

Longevity.Technology - Latest News, Opinions, Analysis and Research

4DMT reports positive interim Phase 1 AEROW data for 4D-710 in cystic fibrosis lung disease

2025-12-19

Benzinga.com

BlackBerry, FedEx, Nike And Other Big Stocks Moving Lower In Friday's Pre-Market Session

2025-12-19

Company data provided by crunchbase