Tango Therapeutics · 2 days ago
Senior Manager, Statistical Programming
Boston, MA
Full-time
Onsite
Senior Level, Lead/Staff
$158K/yr - $236K/yr
8+ years expTango Therapeutics is a biotechnology company dedicated to discovering novel drug targets and delivering the next generation of precision medicine for the treatment of cancer. They are seeking a Senior Manager, Statistical Programming to lead statistical programming activities for clinical trials, ensuring high-quality deliverables and compliance with regulatory standards.
BiotechnologyHealth CareMedicalTherapeutics
Responsibilities
Lead the statistical programming activities for clinical trials and studies, ensuring high-quality and timely deliverables for CSR, publications, presentations, various reports for health authority submissions, clinical data review, and ad hoc analysis
Develop, validate, and maintain analysis datasets (SDTM, ADaM), tables, listings, and figures (TLFs), in accordance with regulatory guidelines and internal standards
Review key clinical study or program documents
Perform complex statistical analyses and simulations using SAS or R to support clinical trial design and data interpretation; manage macro library and templates for efficiently preparing, processing, analyzing clinical data and validating analysis results
Provide expertise in statistical programming for regulatory submissions (e.g., FDA, EMA), including electronic submission standards (eCTD)
Collaborate with biostatisticians, data managers, and cross-functional team members to define programming strategies and requirements, establish project timelines, and perform statistical analyses
Author or review SDTM and ADaM specifications to ensure compliant to CDISC standards
Develop SAS or R code, manage macro or utilities library and templates for efficiently preparing, processing, analyzing clinical data, and validating analysis results
Author and review statistical analysis related SOPs
Stay current with industry trends, best practices, and emerging technologies in statistical programming and data analysis
Additional duties and responsibilities as required
Qualification
Required
Bachelor's or master's degree in statistics, life sciences, computer science, or related field with at least 8 years' statistical programming experience
Solid understanding of industry standards applicable to clinical study data and regulatory reporting requirements including eCTD and CDISC implementation
Expert level in SAS programming (Base, Macro, STAT, GRAPH, SQL) is essential; with experience delivering complex programming assignments, macros, and analyses
Extensive experience in clinical studies including programming and validation of SDTM and ADaM data sets, tables, listings and figures
Expertise in the requirements and technology to support electronic submissions
Strong analytical and communication skills
Preferred
Experience in oncology
Experience with R is desirable
Experience with BLA, NDA/sNDA submissions to FDA/EMA preferred
Company
Tango Therapeutics
Tango Therapeutics is a biotechnology company that is developing next generation cancer therapies.
51-200 employees
H1B Sponsorship
Tango Therapeutics has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (1)
2024 (2)
2023 (1)
2022 (2)
2021 (1)
2020 (3)
Funding
Current Stage
Public CompanyTotal Funding
$548MKey Investors
Nextech InvestBoxer CapitalCasdin Capital
2025-10-23Post Ipo Equity· $197M
2021-08-11Post Ipo Equity· $186M
2021-08-11IPO
Leadership Team
Barbara Weber
President and CEO
Jannik N. Andersen
Chief Scientific Officer
Recent News
2026-01-06
2026-01-05
2025-12-27
Company data provided by crunchbase