Arrowhead Pharmaceuticals · 2 weeks ago
Senior Scientist / Principal Scientist, Clinical Pharmacology
San Diego, CA
Full-time
Hybrid
Senior Level, Lead/Staff
$120K/yr - $170K/yr
3+ years expArrowhead Pharmaceuticals is a clinical stage biopharmaceutical company focused on developing innovative RNAi-based therapeutics for genetic diseases. The Senior Scientist / Principal Scientist in Clinical Pharmacology will lead clinical pharmacology efforts for development programs, contributing to trial design and analysis to guide dosing and regulatory submissions.
BiotechnologyHealth CareNanotechnologyPharmaceutical
Responsibilities
Provide Clinical Pharmacology and pharmacometrics leadership for designated programs, contribute to design of clinical trial protocols and relevant sections in Investigational Brochure (IB), conduct hands-on analysis of clinical or translational PKPD data, support dosing strategies and clinical pharmacology planning. Authorize clinical PK analysis reports and relevant sections in the Clinical Study Report (CSR)
Provide high quality documentation of clinical pharmacology analysis compatible with global regulatory submission requirements. Authorize clinical pharmacology modules of CTD to support global filings of marketing application
Provide timely communication of analysis results and interpretation with drug development teams
Maintain a current understanding of clinical pharmacology literature and regulatory guidance for oligonucleotide/RNAi therapeutics
Qualification
Required
PhD or PharmD in the field of pharmacokinetics, pharmacology or pharmaceutical science
3 years of pharmaceutical industry experience in clinical-stage drug development
Good understanding of FDA/EMA/ICH guidance related to clinical pharmacology
Established experience in clinical NCA PK analysis and data reporting using Phoenix WinNonlin with familiarity of authorizing PK study report
Proficiency in NONMEM and skill of population PKPD modeling is essential
Preferred
PBPK/PD modeling
Benefits
Competitive salaries
Excellent benefit package
Company
Arrowhead Pharmaceuticals
Arrowhead Pharmaceuticals is a biotechnology company that focuses on the development of medicine to treat diseases with a genetic origin.
501-1000 employees
H1B Sponsorship
Arrowhead Pharmaceuticals has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (4)
2024 (5)
2023 (1)
2022 (5)
2020 (1)
Funding
Current Stage
Public CompanyTotal Funding
$2.45BKey Investors
Sarepta TherapeuticsSixth StreetSilence Therapeutics
2026-01-07Post Ipo Equity· $200M
2026-01-07Post Ipo Debt· $625M
2024-11-26Post Ipo Equity· $325M
Leadership Team
Christopher Anzalone
President and Chief Executive Officer
Bruce Given
Chief Operating Officer
Recent News
2026-01-08
2026-01-07
Company data provided by crunchbase