Principal Software Engineer jobs in United States
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Microsoft · 8 hours ago

Principal Software Engineer

Microsoft is an interdisciplinary team focused on developing next-generation AI for precision healthcare. The role involves collaborating with scientists and engineers to design and implement sophisticated machine learning systems and to partner with external organizations for model deployment and improvement.

Agentic AIApplication Performance ManagementArtificial Intelligence (AI)Business DevelopmentDevOpsInformation ServicesInformation TechnologyManagement Information SystemsNetwork SecuritySoftware
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Growth Opportunities
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H1B Sponsor Likelynote

Responsibilities

Design engineering strategy and implement software infrastructures for rapid development and experimentation of sophisticated machine learning systems with large datasets
Collaborate with external partners (healthcare providers, pharmaceutical companies, biotech, etc.) to deploy and improve our models, tools and assets
Collaborate with cross-functional teams to design and implement state-of-the-art systems by considering medical factors and responsible AI principles

Qualification

CC++C#JavaPythonAI applicationsClinical trial softwareNatural language processingDeep learningBiomedical researchInnovationCollaborationProblem-solving

Required

Bachelor's Degree in Computer Science or Biomedical field AND 5+ years technical engineering experience with coding in languages including, but not limited to, C, C++, C#, Java, JavaScript, or Python OR equivalent experience

Preferred

Master's Degree in Computer Science or Biomedical field AND 7+ years technical engineering experience with coding in languages including, but not limited to, C, C++, C#, Java, JavaScript, or Python OR Bachelor's Degree in Computer Science or related technical field AND 12+ years technical engineering experience with coding in languages including, but not limited to, C, C++, C#, Java, JavaScript, or Python OR equivalent experience
3+ years of experience in AI applications to real-world data and real-world evidence, including use cases related to biomedical research and clinical development
3+ years of experience in clinical trial software development and deployment

Benefits

Certain roles may be eligible for benefits and other compensation.

Company

Microsoft

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Microsoft is a software corporation that develops, manufactures, licenses, supports, and sells a range of software products and services.

H1B Sponsorship

Microsoft has a track record of offering H1B sponsorships. Please note that this does not guarantee sponsorship for this specific role. Below presents additional info for your reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (9192)
2024 (9343)
2023 (7677)
2022 (11403)
2021 (7210)
2020 (7852)

Funding

Current Stage
Public Company
Total Funding
$1M
Key Investors
Technology Venture Investors
2022-12-09Post Ipo Equity
1986-03-13IPO
1981-09-01Series Unknown· $1M

Leadership Team

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Satya Nadella
Chairman and CEO
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Vukani Mngxati
Chief Executive Officer - Microsft South Africa
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Company data provided by crunchbase