Mirum Pharmaceuticals, Inc. · 6 hours ago
Senior Director, Program Management
Mirum Pharmaceuticals is a biopharmaceutical company dedicated to transforming the treatment of rare diseases. They are seeking a strategic and operationally-savvy leader to oversee and drive the program management function, establishing best-in-class practices and fostering strong partnerships across teams to ensure program success.
BiotechnologyHealth CarePharmaceuticalTherapeutics
Responsibilities
Lead a high-performing Project Management Office that supports strategic planning and execution across all development programs
Establish and manage program governance to enable prioritization of resources and activities including the facilitation of annual operating plan process in conjunction with FP&A
Develop, implement and continuously refine PMO processes, frameworks and tools (e.g., timelines, stage-gates, communication plans, resource planning, budgeting, decision-making, etc.)
Serve as a strategic partner and communicator with senior leadership: provide program status, decision-support, trade-offs, and portfolio linkage
Facilitate decision-making processes, including risk mitigation strategies and scenario planning
In partnership with program managers, identify key hurdles across programs
Identify, assess and proactively mitigate portfolio-level program risks and dependencies; escalate issues appropriately
Maintain continuous communication with Program Leads to ensure timely support and proactive involvement in program dynamics and team performance
Drive cross-functional collaboration: align stakeholders (clinical, regulatory, CMC, finance, commercial) around program strategy and deliverables
Mentor and develop program managers, fostering a culture of accountability, innovation, and continuous improvement
Coach and mentor PT members on their roles, team interactions, program deliverables & interdependencies, action plans, presentations (executive style) to senior management
Actively resolve issues and elevate concerns with a sense of urgency to promote a culture of rapid improvement and responsiveness
Serve as the Program Manager for one of Mirum’s programs or during corporate development evaluation of potential new assets, as needed
Qualification
Required
Bachelor's degree in life sciences, engineering or related field required
10+ years of experience in the biotech or pharmaceutical industry, with substantive exposure to drug (or biologic/therapy) development
Demonstrated portfolio and program management experience with cross-functional and global teams, including milestone budget/resourcing management
Deep understanding of the therapeutic development lifecycle, including non-clinical, clinical, CMC/manufacturing, regulatory and commercial interface
Excellent leadership, communication and interpersonal skills: ability to influence without direct authority, build relationships across functions and navigate matrix environments
Strong analytical and problem-solving capabilities; comfortable with ambiguity and dynamic change
Familiarity with program management tools and frameworks (e.g., MS Project, Smartsheet, stage-gate process)
Preferred
advanced degree (MS, PhD, MBA) strongly preferred
Previous experience building a PMO is a plus
Company
Mirum Pharmaceuticals, Inc.
Mirum Pharmaceuticals, Inc. is a biopharmaceutical company dedicated to transforming the treatment of rare diseases affecting children and adults.
H1B Sponsorship
Mirum Pharmaceuticals, Inc. has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (1)
2024 (2)
2023 (1)
2022 (1)
2021 (1)
2020 (1)
Funding
Current Stage
Public CompanyTotal Funding
$765.5MKey Investors
TCG CrossoverOberland CapitalNew Enterprise Associates
2025-12-19Post Ipo Equity· $68.5M
2025-12-08Post Ipo Equity· $200M
2023-04-12Post Ipo Equity· $275M
Recent News
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2026-01-14
2026-01-13
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