Bioinformatics Engineer jobs in United States
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Manifold Bio · 1 month ago

Bioinformatics Engineer

positionBoston
timeFull-time
remoteOnsite
senioritySenior Level
date7+ years exp

Manifold Bio is a dynamic biotech company focused on targeted biologics using a novel in vivo-centric discovery approach. The Bioinformatics Engineer will collaborate with computational and experimental scientists to build infrastructure and extract insights from Next Generation Sequencing data, developing advanced algorithms and deploying bioinformatics data pipelines for wet lab scientists.

BiotechnologyHealth CarePharmaceuticalTherapeutics
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H1B Sponsor Likelynote

Responsibilities

Refine and improve central Python NGS infrastructure
Implement advanced counting algorithms for Illumina and Oxford Nanopore sequencing readouts
Support custom bioinformatics projects such as RNA-seq and scRNA-seq experiments
Deploy bioinformatics data pipelines as self-serve workflows for wet lab scientists
Support in NGS data management of dozens of terabytes of raw data

Qualification

Next Generation SequencingPython developmentBioinformatics data pipelinesAWSWorkflow orchestratorsStatistics fundamentalsCloud computingData visualizationCommunication skills

Required

PhD in computational biology or bioinformatics, or B.S. with 7+ years of equivalent experience in computational biology or bioinformatics
Experience working with Next Generation Sequencing (NGS) data from library-based experiments
Strong Python development skills
Experience with translating and scaling local workflows onto AWS
Deep knowledge of version control, test-driven development, and cloud computing
Experience working with workflow orchestrators/engines
Strong understanding of statistics fundamentals and data analysis methodologies
Outstanding written and verbal communication skills for cross-functional collaboration

Preferred

Industry experience in antibody therapeutic development or biotechnology R&D
Experience building and supporting custom single cell sequencing workflows
Experience with robust code package development, CI/CD
Track record of developing computational tools or pipelines adopted by experimental teams
Experience mentoring junior scientists or leading cross-functional project teams
Publications or patents in antibody engineering, protein design, or high-throughput screening methods
Familiarity with cloud computing platforms (AWS, GCP) and containerization technologies
Experience with Tableau and other data visualization packages

Company

Manifold Bio

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Manifold Bio is building a protein barcoding platform to bring the power of multiplexed measurement.
dateFounded in 2020
location
Boston, Massachusetts, USA
people-size11-50 employees
web-link
https://manifold.bio/

H1B Sponsorship

Manifold Bio has a track record of offering H1B sponsorships. Please note that this does not guarantee sponsorship for this specific role. Below presents additional info for your reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2024 (1)
2023 (1)
2021 (1)

Funding

Current Stage
Early Stage
Total Funding
$46.4M
Key Investors
Amazon Web ServicesTriatomic CapitalPlayground Global
2025-10-08Non Equity Assistance· $1M
2022-06-13Series A· $40M
2020-09-11Seed· $5.4M

Leadership Team

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Gleb Kuznetsov
Co-Founder and CEO
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Pierce Ogden
Co-Founder & CTO
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Recent News

BioSpace
Roche Spends $570M on Another ADC Agreement With China’s MediLink
2026-01-11
BioSpace
Roche Makes Good on Dealmaking Promise With $1.1B Caris Cancer Collab
2025-12-17
Business Wire
Manifold Bio Expands Leadership Team to Drive its AI + In Vivo Targeted Biologics Platform
2025-12-15
Company data provided by crunchbase