Associate Engineer II (contract), Polysaccharide Pilot Plant Process Development jobs in United States
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Vaxcyte · 2 weeks ago

Associate Engineer II (contract), Polysaccharide Pilot Plant Process Development

Vaxcyte is a clinical-stage vaccine innovation company focused on developing high-fidelity vaccines against bacterial diseases. They are seeking an Associate Engineer II to support the Polysaccharide Upstream Pilot Plant by executing experiments related to polysaccharide production and contributing to process characterization.

BiopharmaBiotechnologyHealth Care
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Comp. & Benefits
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H1B Sponsor Likelynote

Responsibilities

Perform experiments for polysaccharide upstream process such as fermenters, centrifuges, depth filtration, and tangential flow filtration operations
Support media and buffer preparations for the experiments for execution
Perform assays needed to analyze the results of the experiment such as metabolite analysis for fermentation and colorimetric plate assays to determine concentrations of product and impurities through the operations
Assist in design and execution of upstream process development studies, including protocols and reports
Keep accurate and current records of development experiments and/or project related activities in an electronic laboratory notebook
Present data from experiments to the team and contribute to technical discussions
Work within a team environment and provides support as necessary to further the team’s initiatives

Qualification

Upstream process experienceColorimetric plate assaysGxP environment knowledgeMicrosoft ExcelDesign of Experiments (DoE)Interpersonal skillsWritten communicationVerbal communication

Required

BS in Chemical Engineering, Biochemistry, or a related discipline, with minimum 2 years of relevant industry experience. MS without experience; or equivalent work experience
Strong experience with at least 2 upstream operations: single-use fermentors, centrifuges, depth filtration, and tangential flow filtration
Experience executing colorimetric plate-based assays and routine biological operations analyses such metabolite, pH, and turbidity monitoring
Experience in writing experimental protocols and summary reports, as well as presenting data for discussion
Proficient with computer programs such as Microsoft Excel, Word, PowerPoint
Experience in a GxP environment and working knowledge of the requirements of GMPs
Working knowledge of use of an electronic laboratory notebook
Familiarity with DoE (Design of Experiments) and application of statistics
Strong interpersonal skills to collaborate well within the team and excellent written and verbal communication skills
Must be flexible with working hours as needed for the experiments
Polysaccharide team members require booster vaccination with PCV

Preferred

Centrifugation experience is a plus
Bradford and Lowry assays are a plus
Benchling experience is a plus

Company

Vaxcyte

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Vaxcyte focuses on developing vaccines designed to prevent or treat some of the most common and deadly infectious diseases worldwide.

H1B Sponsorship

Vaxcyte has a track record of offering H1B sponsorships. Please note that this does not guarantee sponsorship for this specific role. Below presents additional info for your reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (14)
2024 (7)
2023 (5)
2022 (7)
2021 (2)

Funding

Current Stage
Public Company
Total Funding
$3.85B
Key Investors
CARB-XTPG GrowthAbingworth
2024-09-04Post Ipo Equity· $1.5B
2024-01-30Post Ipo Equity· $862.5M
2023-04-19Post Ipo Equity· $500M

Leadership Team

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Andrew Guggenhime
President & Chief Financial Officer
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Jeff Fairman
Founder and Vice President, Research
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Company data provided by crunchbase