Revolution Medicines · 2 days ago
Vice President, Structural and Molecular Sciences
San Francisco Bay Area
Full-time
Onsite
Director/Executive
$294K/yr - $367K/yr
15+ years expRevolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies for RAS-addicted cancers. The VP of Structural and Molecular Sciences will lead a group in protein science and structural biology, drive innovation in drug discovery, and manage a high-performing team to advance transformative science.
Health CareLife ScienceMedical
Responsibilities
Collaborate with Research leadership to develop a long-term strategy for portfolio expansion through discovery of inhibitors of frontier oncology targets
Partner with digital drug discovery and AI/ML teams to harness data analytics at all stages of discovery, and particularly data-informed approaches to accelerate DMTA cycles
Provide vision and leadership to a dynamic group of scientists to implement strategy
Drive cross-functional alignment to support a dynamic portfolio of discovery and development stage projects
Actively participate in cutting edge research, particularly at the earliest stages of drug discovery, where failure rate is high and creativity and innovation are key
Mentor scientists to ask and answer the right questions in this environment
Bring expertise in assay development, data acquisition, screening, and advanced analytical methods, as well as a rigorous, output-focused approach to science
Champion applying advanced analytic methods to predictive molecular design and automation and computational methods to increase throughput and reproducibility
Collaborate with the external scientific community to advance state of the art structural and chemical biology methods to inform innovation internally
Manage a high-performing group with multiple functions and talented Ph.D. and non-Ph.D. scientists at many career levels
Sustain productivity through strategic hiring, mentoring, and support for individual career growth
Be accountable for an annual budget
Position the Structural and Molecular Sciences function as a bridge across Research, enabling bench-to-bedside insights
Partner with Medicinal Chemistry, Digital Drug Discovery, Systems Biology, and Translational Research to identify molecular determinants of response, resistance, and target vulnerability and to inform discovery priorities
Contribute to organizational excellence and rigor by being curious and asking questions of diverse subject matter experts
Serve as a visible leader representing Revolution Medicines’ scientific excellence internally and externally
Qualification
Required
Ph.D. in Biochemistry, Chemical Biology, Biophysics, Structural Biology, or related discipline
Minimum of 15 years of experience in molecular science-related disciplines in the biotech industry, with experience in small molecule drug discovery at the target ID, hit ID, and early discovery stages
10 years of experience with functional group management, including mentorship, budgets and strategic planning
Demonstrated ability to build, lead, and foster a collaborative culture on interdisciplinary teams
Ability to work in a high-energy, fast-paced, rapidly evolving and scaling company, operating in a highly competitive field
Track record of cross-functional leadership within integrated discovery and translational environments
Excellent written and verbal communication skills with ability to clearly convey complex concepts to specialist and non-specialist audiences
Preferred
Experience with molecular glue drug discovery
Familiarity with drug discovery for oncology
Proven track record of advancing research programs from discovery to development, including experience collecting data and preparing materials for IND submission
Fluency in modern data systems and analytics, with experience implementing and managing these systems in industry
Benefits
Competitive cash compensation
Robust equity awards
Strong benefits
Significant learning and development opportunities
Company
Revolution Medicines
Revolution Medicines is an innovative and dynamic organization of expert biologists, chemists, pharmacologists, clinical scientists.
501-1000 employees
H1B Sponsorship
Revolution Medicines has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (13)
2024 (18)
2023 (15)
2022 (8)
2021 (1)
2020 (2)
Funding
Current Stage
Public CompanyTotal Funding
$2.25BKey Investors
Royalty PharmaBoxer CapitalNextech Invest
2025-06-24Post Ipo Debt· $250M
2024-12-02Post Ipo Equity· $750M
2023-03-02Post Ipo Equity· $323.6M
Leadership Team
Luan Wilfong
Chief Human Resources Officer
Steve Kelsey
President
Recent News
Pharmaceutical Technology
2026-01-13
Company data provided by crunchbase