Lyterian Therapeutics ยท 1 month ago
Senior Scientist/Principal Scientist, Oncology
South San Francisco, CA
Full-time
Onsite
Senior Level
$155K/yr - $205K/yr
4+ years expLyterian Therapeutics is committed to developing medicines for patients in need by utilizing protein homeostatic mechanisms. The Senior Scientist/Principal Scientist in Oncology will design and execute screening assays, collaborate with a diverse scientific team, and contribute to the company's intellectual property in the field of oncology research.
BiotechnologyLife ScienceMedical
Responsibilities
Design and execute cell-based assays to interrogate target biology and advance our drug discovery programs
Use automation, high-content microscopy, and/or flow cytometry to develop our proprietary platform
Use functional genomics, proximity labeling, and/or chemoproteomics approaches to understand the mechanistic basis of hit compounds emerging from our proprietary platform
Develop and contribute to company's intellectual property (IP) domain by way of patents and/or publications
Stay up-to-date with emerging scientific literature and share your ideas liberally
Collaborate and communicate across a diverse scientific team to successfully progress Lyterian goals
Qualification
Required
PhD in biology, biochemistry, or related field with 4-8 years of industrial or postdoctoral experience in drug discovery and/or cancer biology
Demonstrated expertise in mammalian cell culture techniques including transfection and transient or stable expression of recombinant proteins, CRISPR/Cas9 gene editing, plasmid design, siRNA and shRNA knockdown, cell proliferation and viability analysis
Demonstrated expertise in molecular biology techniques including but not limited to: in vitro enzymatic assays, IP assays, qPCR, western blots, FACS, IHC, ELISA, HTRF
RNA and protein isolation from tumor samples
Familiarity with in vivo tumor models
Proficiency in analyzing data with GraphPad Prism and other analysis programs
Keen analytical and problem-solving skills, and the ability to resolve routine issues using appropriate information
Evidence of scientific excellence and impact as illustrated by scientific publications and presentations
Understanding of the drug development process
Initiative and boldness to dive into a fast-paced new startup
Preferred
Bioinformatics expertise is a plus
Benefits
Annual bonus
Significant equity
Comprehensive health, dental, and vision insurance for our employees and their families
401K match
Company
Lyterian Therapeutics
Lyterian Therapeutics focused on developing new drugs for diseases by using natural mechanisms of protein regulation.
11-50 employees
H1B Sponsorship
Lyterian Therapeutics has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2024 (2)
2023 (1)
Funding
Current Stage
Early StageLeadership Team
Michael Rape
Co-Founder
Recent News
2025-04-16
Company data provided by crunchbase