Beth Israel Lahey Health · 1 month ago
Bioinformatician and Data Infrastructure Lead
Beth Israel Lahey Health is a growing healthcare organization that aims to make a difference in people’s lives. They are seeking a Bioinformatician / Data Infrastructure & Analytics Lead who will drive the lab’s computational strategy and data ecosystem, establishing lab-wide data standards and developing integrative analytic frameworks that support high-impact research and translational discovery.
Elder CareHealth CareHospitalPrimary and Urgent CareProfessional ServicesTraining
Responsibilities
Leads projects associated with the design, development and maintenance of data collection instruments, databases and procedure manuals
Leads the design and implements, performs data management and quality control procedures as necessary for routine and special projects
Creates novel computational approaches and analytical tools as required by research goals
Analyzes large molecular datasets such as raw microarray data, genomic sequence data, and proteomics data for clinical or basic research purposes
Independently develops computational systems to allow comparison or integration of data from multiple sources. Supports the creation of such applications in support of research projects
Leads and collaborates with program staff on the design and analysis of biostatistics aspects of research protocols. Participates in the design of questionnaires and interview forms
Compiles data for use in activities such as gene expression profiling, genome annotation, and structural bioinformatics . Provides statistical and computational tools for biologically based activities such as genetic analysis, measurement of gene expression, and gene function determination
Analyzes data beginning with univariate and multivariate analyses such as logistic regression and factor analysis for research studies. Supports the interpretation and assists in the creation of study results in collaboration with faculty members, epidemiologists, biostatisticians and other team members
Provides tabular and graphic summaries of analyses in a form suitable for inclusion in manuscripts for publication in peer reviewed scientific journals as well as for presentation at scientific meetings
Travels to project specific administrative and or national clinical meetings and presents findings. Attends project team meetings as needed
Has the authority to direct and support employees daily work activities. Has authority to undertake or recommend the following employment actions: hiring, termination, corrective action and performance reviews. Direct Reports: None Indirect Reports: None
Assists in planning, monitoring and/or managing budget in functional area of department
Qualification
Required
Doctoral degree in Computational Biology, Bioinformatics, or related field required
5-8 years related work experience required in Integration of multiple complex NGS datasets including RNA-Seq, ChIP-Seq, ATAC-seq, CUT&RUN, and atlas-scale single cell/nucleus sequencing data and 1-3 years supervisory/management experience required
Must be able to apply existing algorithms in the analysis of such data and, if necessary, derive novel programs. These include expertise in multivariable regression analyses, ChIP/ATAC peak calling, comprehensive motif analyses (discovery, enrichment, etc.), and single cell deconvolution and clustering
Must have experience in performing bioinformatic analyses for a core, including acting as a liaison to core clients/users. Must have demonstrated facility in providing bioinformatic consultation, including translation of a user goals into a clear bioinformatic output. As such, should show evidence of authorship or attribution on multiple manuscripts
Advanced skills with Microsoft applications which may include Outlook, Word, Excel, PowerPoint or Access and other web-based applications. May produce complex documents, perform analysis and maintain databases
Preferred
Advanced skills with Microsoft Excel, PowerPoint and other web-based applications. May produce complex documents, perform analysis and maintain databases
Specific skills using R/Bioconductor, Seurat, Picard, and CellBender preferred. Experience with online visualization tools for biological data, such as UCSC Genome Browser, Morpheus, and Single-Cell Portal
Should be able to clearly delineate and explain the goals, relative strengths/weaknesses of various possible computational algorithms to biologists without bioinformatic experience
Company
Beth Israel Lahey Health
Beth Israel Lahey Health Center offers patient care, urgent care, assisted living, and research and education services.
H1B Sponsorship
Beth Israel Lahey Health has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
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Trends of Total Sponsorships
2024 (2)
2022 (1)
Funding
Current Stage
Late StageRecent News
Boston Globe
2025-11-24
Morningstar.com
2025-11-07
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