Merck · 1 day ago
Principal Scientist, Respiratory Diseases
South San Francisco, CA
Full-time
Hybrid
Lead/Staff
$173K/yr - $272K/yr
8+ years expMerck is a large pharmaceutical company seeking an experienced scientist to drive innovation in respiratory medicine. The role involves leading the discovery and development of novel respiratory medicines and collaborating across various teams to advance pipeline programs.
BiotechnologyHealth CareMedicalPharmaceutical
Responsibilities
Lead or contribute to the discovery and development of novel respiratory medicines, from early research up to clinical development
Design and execute strategies for target identification, validation, and translational approaches in respiratory disease areas (e.g., COPD, asthma, pulmonary hypertension, NCFBE)
Effectively manage and lead multiple projects, including experimental design, resource allocation, and timeline adherence, ensuring milestones are met and risks are proactively addressed
Collaborate cross-functionally with medicinal chemistry, pharmacology, clinical, and regulatory teams to advance pipeline programs
Interpret complex data sets and provide scientific leadership to guide decision-making
Stay current on emerging science, competitive landscape, and regulatory requirements in respiratory therapeutics
Manage and mentor junior scientists and foster a culture of innovation and collaboration
Qualification
Required
Ph.D., Pharm.D. or M.D. in biology, pharmacology or related discipline and eight (8) years of respiratory drug development experience
Proven track record of advancing respiratory programs from discovery through clinical phases
Strong understanding of respiratory disease biology, pharmacology, and translational science
Excellent communication and leadership skills; ability to influence across functions
Disease Research
Pharmacology
Project Leadership
Pulmonary Disease Research
Pulmonology
Respiratory Pharmacology
Translational Research
Preferred
Deep understanding of the disease biology and pathophysiology for one or more respiratory diseases
Experience with inhaled drug delivery systems and formulation development
Proficiency in pharmacology, PK/PD modeling, and translational science for respiratory indications
Familiarity with preclinical models of respiratory diseases and biomarker strategies
Knowledge of regulatory requirements and clinical development considerations for respiratory medicines
Ability to leverage data analytics and digital tools to support decision-making
Benefits
Medical
Dental
Vision healthcare and other insurance benefits (for employee and family)
Retirement benefits, including 401(k)
Paid holidays
Vacation
Compassionate and sick days
Company
Merck
Merck is a biopharmaceutical company that offers medicines and vaccines for various diseases.
10001+ employees
Funding
Current Stage
Public CompanyTotal Funding
$5.59MKey Investors
Private Capital AdvisorsGavi, the Vaccine Alliance
2018-11-25Post Ipo Equity· $0.59M
2016-01-21Series Unknown· $5M
1980-12-19IPO
Leadership Team
Betty Larson
Executive Vice President and Chief Human Resources Officer
Dean Li
Executive Vice President and President, Merck Research Laboratories
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