Vivodyne · 1 month ago
Principal Mechanical Engineer – Advanced Automation & Systems Integration
Brisbane, CA
Full-time
Onsite
Senior Level, Lead/Staff
$222K/yr - $308K/yr
6+ years expVivodyne is a company focused on creating human data before clinical trials through advanced automation and systems integration. As a Principal Mechanical Engineer, you will develop and optimize hardware and software for robotic systems that enhance biological workflows, collaborating with a multi-disciplinary team to drive innovation in drug discovery.
Artificial Intelligence (AI)BiotechnologyLifestyle
Responsibilities
Architect, design, and implement advanced automation systems, ranging from automated microfluidic manufacturing to high-precision mammalian cell culture platforms—all of which are mission-critical and highly visible both internally and externally
Develop hardware and software systems that acquire and process data reliably, ensuring smooth handoffs to production through rigorous documentation, data acquisition, and analysis
Embrace the dynamic nature of a rapidly growing startup, working across multiple projects and disciplines
Collaborate cross-functionally with Product leads, tissue engineers, microfluidics specialists, and AI researchers etc. to gather requirements, set technical objectives, and integrate new features into our robotics platforms
Design and implement resilience mechanisms to ensure system robustness, enabling fault detection, fault recovery, and minimal downtime, while maintaining data integrity
Proactively identify optimization opportunities, selecting priorities through engineering analysis and data-driven decision-making
Communicate progress and findings to internal stakeholders—including mechanical engineers, data scientists, and senior leadership—through data-laden presentations and technical reports
Qualification
Required
Bachelor's degree in Mechanical Engineering, Chemical Engineering, or a related field with a focus on microfluidics, tissue engineering, or lab automation
At least six years of directly relevant industry experience
Broad experience in hardware and software design for automation
Proficiency in key hardware and software tools, including SolidWorks (expert-level, CAM experience is a plus)
Exposure to Python/Matlab/C++/C#/Javascript/etc
Hands-on experience with commonly used automation hardware, such as vision/camera systems, motion control, liquid handling, and pick-and-place robotics
Highly knowledgeable in various Manufacturing Technologies
Strong ownership mentality, ensuring the timely delivery of high-reliability features and improvements
A team player, capable of working with engineers, scientists, and external stakeholders
Clear communicator, able to explain complex robotics concepts to cross-functional teams
Passionate about staying at the cutting edge of robotics
Preferred
M.S. or Ph.D. in Mechanical Engineering, Chemical Engineering, or a related field
Experience in biotech/lab automation or semiconductor robotics
Knowledge of microfluidics and fluid handling systems
Experience integrating robotics with high-content imaging and confocal microscopy systems
Biology background or familiarity with cell and tissue engineering concepts
Experience with electronics/PCBA design or basic knowledge (reading schematic, troubleshooting interconnects)
Statistical analysis/data collection to inform design performance rigorously
Company
Vivodyne
Vivodyne accelerates drug discovery using lab-grown human tissues, robotics, and AI to generate accurate preclinical test data.
11-50 employees
H1B Sponsorship
Vivodyne has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2024 (2)
Funding
Current Stage
Early StageTotal Funding
$80MKey Investors
Khosla Ventures
2025-05-29Series A· $40M
2023-11-22Seed· $38M
2021-03-11Seed· $2M
Leadership Team
Andrei Georgescu, Ph.D.
Chief Executive Officer
Sheila Ahern
Senior Executive Assistant to Chief Executive Officer & C-Suite
Recent News
2025-10-16
Technically Media
2025-06-28
Tech Startups - Startups and Technology news
2025-06-11
Company data provided by crunchbase