Senior Computational Biologist I jobs in United States
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Freenome · 1 week ago

Senior Computational Biologist I

Freenome is seeking a Senior Computational Biologist to join their Computational Biology, Assay Development team. The role involves applying scientific expertise to develop early, noninvasive tests for cancer detection, collaborating cross-functionally to ensure successful development of molecular assays for diagnostic products.

BiotechnologyHealth CareHealth DiagnosticsOncologyPersonal Health
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Comp. & Benefits
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H1B Sponsor Likelynote

Responsibilities

Plan and execute development experiments for Freenome’s multiomics cancer screening tests
Partner cross-functionally with computational, development, regulatory, and quality leaders to develop and execute a regulated development strategy working toward FDA approval
Use your quantitative skills to develop computational methods and interpret complex experimental results in order to optimize and validate innovative technology for sample collection, preparation, and detection
Develop and execute appropriate experimental design and analysis plans for Development, Verification, and Validation studies, closely partnering with Biostatistics, Development, and Pre-Analytics teams
Work closely with molecular and computational research teams developing Freenome’s IVD products for blood-based molecular assays involving cell-free DNA
Impact patient lives through the development and launch of high quality cancer screening technologies

Qualification

Computational BiologyBioinformaticsMolecular BiologyNext Generation SequencingExperimental DesignApplied StatisticsData AnalysisData VisualizationCommunication SkillsCollaboration Skills

Required

Post-graduate degree (MS or PhD) in statistics, computational biology, bioinformatics, cancer biology, or related quantitative field
3+ years of industry experience
Experience with molecular biology and next generation sequencing
Experience in experimental design and analysis of high-throughput, quantitative technologies
Familiarity with and ability to select and leverage bioinformatics tools for the above molecular assays
Experience in applied statistics, such as in hypothesis testing, GLM, and appropriate use of simulation
Expertise in data analysis and visualization using R (tidyverse), or Python statistical packages (Numpy, Matplotlib, Pandas), or equivalent, under version control
Excellent oral and written communication skills to communicate to scientific and broader audiences, with keen attention to detail
Ability to work on a cross-functional team in our highly collaborative environment, working with both computational and experimental scientists

Preferred

Experience in the development of diagnostic devices in a regulated environment (PMA, 510(k), CE-IVD) preferred
Experience with a variety of NGS methods (e.g., WGS, target capture with UMI, bisulfite sequencing, RNA-seq)

Benefits

Equity
Cash bonuses
Full range of medical, financial, and other benefits

Company

Freenome

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Freenome is a biotechnology company developing blood tests for early cancer detection to improve access to routine screening.

H1B Sponsorship

Freenome has a track record of offering H1B sponsorships. Please note that this does not guarantee sponsorship for this specific role. Below presents additional info for your reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (7)
2024 (11)
2023 (15)
2022 (10)
2021 (7)
2020 (7)

Funding

Current Stage
Late Stage
Total Funding
$1.53B
Key Investors
RocheExact SciencesS32
2025-12-04Acquired
2025-11-17Corporate Round· $75M
2025-08-06Corporate Round· $50M

Leadership Team

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Aaron Elliott
Chief Executive Officer
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Riley Ennis
Co-Founder
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Company data provided by crunchbase