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Calico Life Sciences · 1 month ago

Intern, Protein Biochemistry - Structural Biology (BS)

South San Francisco, CA

Internship

Onsite

Intern

$45/hr - $70/hr

Start in 2026 Summer

Calico is seeking an intern to join the Protein Science group. The intern will work on the structural and functional characterization of proteins and collaborate with other groups to provide mechanistic insight into proteins of interest.

Biotechnology

Comp. & Benefits

No H1B

Responsibilities

Express and purify recombinant proteins

Play an active role in structural determination and assessment of protein-protein and protein-ligand interactions

Perform and optimize protein activity and/or binding assays

Communicate scientific results in a group setting

Qualification

Recombinant protein experienceMolecular biology knowledgeProtein biochemistry interestExperimental structural biologyFlexibleMultitaskingTeamwork skillsCommunication skillsDetail-orientedSelf-motivated

Required

Currently pursuing a BS degree in biology, biochemistry, biological sciences or related field

Experience working with recombinant proteins (expression in E. coli and mammalian systems, multi-step-purification, analysis, and structural determination)

Knowledge of general principles of molecular biology and protein biochemistry

A strong interest in protein biochemistry

Detail-oriented and organized

Strong teamwork and communication skills

Self-motivated with a 'can-do' attitude

Flexible, able to respond quickly to shifting priorities and able to multitask

Able to work in-person at our offices in South San Francisco

Free for a consecutive period of 11-12 weeks in June, July, and August

Not graduating before December 2026

Must be enrolled in a US university