Neurocrine Biosciences · 5 hours ago
Executive Director, DMPK
San Diego, CA
Full-time
Onsite
Director/Executive
$277K/yr - $378K/yr
12+ years expNeurocrine Biosciences is a leading neuroscience-focused biopharmaceutical company dedicated to discovering and developing life-changing treatments for patients with neurological disorders. The Executive Director, DMPK will develop strategic plans and lead the Preclinical Pharmacokinetics function, ensuring that clinical candidates are identified and characterized appropriately throughout the development process.
BiotechnologyHealth CarePharmaceutical
Responsibilities
Provides strategic, functional leadership and oversight to the Preclinical Pharmacokinetic function within Preclinical Development
Responsible for the development and enablement of departmental strategies to evaluate Preclinical Pharmacokinetics including ensuring continued expansion and/or updating of training, techniques and/or equipment
Leads and manages the conduct, interpretation and reporting of preclinical pharmacokinetic studies
Works with Research and Preclinical Development colleagues to establish optimal lead candidate characteristics, develop appropriate testing schemes, and design, conduct and report on preclinical studies intended to characterize potential drug candidates
Designs & conducts Preclinical Pharmacokinetic and Toxicokinetic/Pharmacokinetic/Pharmacodynamic studies in support of clinical development compounds
Oversees the preparation of Preclinical Pharmacokinetic sections of regulatory documents (IND, NDA, briefing books, Investigator Brochures, etc.)
Actively leads/participates in research-stage and development-stage program teams from both a strategic and tactical level
Prepares data summaries and presents results to peers, colleagues, the Management Committee and regulatory agencies
Prepares Standard Operating Procedures (SOPs) as needed to guide the Preclinical Pharmacokinetics activities
Performs other duties as assigned
Qualification
Required
Bachelor's in chemistry, life sciences or closely related discipline and 17+ years of pharmaceutical/biotech experience, with extensive management experience
Experience in managing preclinical Contract Research Organizations
Experience managing preclinical scientists and preparation of INDs, CTDs, NDAs, and MAAs
Experience with silico modeling and simulation tools is beneficial OR
MS in Pharmacokinetics, Pharmaceutical Sciences, or closely related discipline and 15+ years of similar experience noted above OR
PhD in Pharmacokinetics, Pharmaceutical Sciences, or closely related discipline or PharmD and 12+ years of similar experience noted above
Demonstrated leadership of a Preclinical Pharmacokinetic function
Extensive experience in managing preclinical Contract Research Organizations
Excellent knowledge of preparation of INDs, CTAs, NDAs, and MAAs
Working knowledge of in silico modeling and simulation tools
Proactive, innovative, with good problem-solving skills
Knowledgeable of and current on regulatory guidance
Acts as a 'trusted advisor' across the company and may be recognized as an external expert
Provides strategy, vision and direction regarding issues that may have company-wide impact
Requires in-depth knowledge of the functional area, business strategies, and the company's goals
Possesses industry-leading knowledge
Ability to work strategically in a cross functional team and matrix environment
Excellent written, presentation, and verbal communication skills
Exceptional leadership, coaching, employee development skills
Demonstrated ability to negotiate and influence others with or without authority at all levels of the organization
Benefits
Annual bonus with a target of 35% of the earned base salary
Eligibility to participate in our equity based long term incentive program
Retirement savings plan (with company match)
Paid vacation
Holiday and personal days
Paid caregiver/parental and medical leave
Health benefits to include medical, prescription drug, dental and vision coverage in accordance with the terms and conditions of the applicable plans
Company
Neurocrine Biosciences
Neurocrine Biosciences engages in the discovery and development of drugs for the treatment of neurological and endocrine-related diseases.
1001-5000 employees
H1B Sponsorship
Neurocrine Biosciences has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (16)
2024 (9)
2023 (8)
2022 (2)
2021 (5)
2020 (6)
Funding
Current Stage
Public CompanyTotal Funding
$260MKey Investors
Venrock
2015-02-19Post Ipo Equity· $250M
2009-12-17Post Ipo Equity· $10M
1996-05-31IPO
Leadership Team
Matt Abernethy
Chief Financial Officer
D
Dimitri Grigoriadis
VP, Research
Recent News
2025-12-24
Company data provided by crunchbase