Research Associate II jobs in United States
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Freenome · 4 hours ago

Research Associate II

Freenome is a company focused on developing genomic assay technologies for early cancer detection. The Research Associate II will contribute to the development of workflows and methodologies in a regulated high throughput environment, collaborating closely with various scientific teams to ensure high-quality data production.

BiotechnologyHealth CareHealth DiagnosticsOncologyPersonal Health
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Comp. & Benefits
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H1B Sponsor Likelynote

Responsibilities

Apply hands-on knowledge of molecular biology, nucleic-acid biochemistry and next generation sequencing to develop and optimize NGS based methods and processes following principles of Design Controls for IVD development
Design and perform experiments to develop and optimize NGS workflow including DNA/RNA extraction, library preparation, target capture, and sequencing
Operate and maintain NGS related instruments such as automated liquid handlers, PCR instruments, and sequencers
Conduct new reagents testing and develop reagent quality control methods
Participate in troubleshooting issues, identify and implement process improvement for the entire analytical workflow
Collaborate with research, computational scientists, and automation engineers to transfer research prototype assays from Research to Development
Collaborate with Quality Control Lab, Manufacturing lab, Quality, and Regulatory to transfer reagent quality control methods and manufacturing processes from Development to Operations and support the implementation of the methods and processes in Operations
Accurately record results in electronic lab notebooks, author work instructions and record forms, contribute to writing study protocols and reports. Diligently apply current Good Laboratory and Documentation Practices (cGLP, cGDP)
Exemplify Freenome cultural values across the organization

Qualification

Next-gen sequencing (NGS)Molecular biologyNucleic acid preparationAutomated liquid handlersData analysisTroubleshootingProgramming (Python/R)Clear communicationAttention to detailCollaboration skills

Required

Bachelor's in molecular biology, biochemistry, or a related field with 2+ years of experience in the life sciences or Master's in molecular biology or a related field
Hands-on experience in Next-gen sequencing (NGS) based automated assay development including extraction, library preparation, target capture, and sequencing
Hands-on experience in nucleic acid preparation, amplification, and quantification (DNA/RNA extraction and purification, PCR, qPCR, ddPCR, Qubit, Fragment Analyzer, Tapestation)
Experience in working with ctDNA/cfDNA as an analyte in NGS workflows
Experience with automated platforms in plate-based, low-volume formats and experience working with automated liquid handlers
High attention to detail and ability to record accurate and detailed observations, assess impact, and perform troubleshooting as required
Ability to perform data analysis and to be critical of results obtained during experimentation
Clear and proactive communication skills and ability to collaborate effectively with team members in the same and adjacent disciplines

Preferred

Experience working in a regulated laboratory environment (CLIA, GLP/GCLP, IVD development) strongly desired
Experience in programing in a scientific programming language (e.g., Python or R)

Benefits

Equity
Cash bonuses
Full range of medical, financial, and other benefits

Company

Freenome

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Freenome is a biotechnology company developing blood tests for early cancer detection to improve access to routine screening.

H1B Sponsorship

Freenome has a track record of offering H1B sponsorships. Please note that this does not guarantee sponsorship for this specific role. Below presents additional info for your reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (6)
2024 (11)
2023 (15)
2022 (10)
2021 (7)
2020 (7)

Funding

Current Stage
Late Stage
Total Funding
$1.53B
Key Investors
RocheExact SciencesS32
2025-12-04Acquired
2025-11-17Corporate Round· $75M
2025-08-06Corporate Round· $50M

Leadership Team

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Aaron Elliott
Chief Executive Officer
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Charles Roberts
Co-Founder
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Company data provided by crunchbase