Manifold Bio · 2 days ago
Head of Biotherapeutics
Boston
Full-time
Onsite
Director/ExecutiveManifold Bio is a dynamic biotech company focused on innovative biologics through in vivo drug discovery. They are seeking a Head of Biotherapeutics to lead the protein therapeutic workflow, drive optimization strategies, and integrate advanced protein engineering technologies into their development pipeline.
BiotechnologyHealth CarePharmaceuticalTherapeutics
Responsibilities
Leading internal protein sciences and protein engineering teams
Own strategy for early stage de-risking and optimization of lead molecules
Own strategy for developability assessment
Work with internal and external team members to ensure cost-effective and timely drug manufacture
Build internal expertise on cutting-edge protein engineering techniques
Guide prioritization for internal protein generation efforts, balancing between screening and lead characterization
Build an R&D-to-development pipeline for lead candidates
Utilize state of the art techniques to drive the development of best-in-class therapeutic candidates
Stay up to speed on cutting edge research and industry standards for protein therapeutics
Qualification
Required
Experience taking multiple molecules through IND and into the clinic
Deep understanding of protein production techniques, including mammalian cell culture and purification/characterization approaches
Expertise in novel biotherapeutic modalities, across a range of formats
Extensive experience leading cross-functional teams
Experience with complex biologics (e.g. multispecifics)
Preferred
Experience with drug development in neuroscience
Experience liaising with CDMOs through IND
Experience with generative AI models for protein design
Company
Manifold Bio
Manifold Bio is building a protein barcoding platform to bring the power of multiplexed measurement.
Founded in 2020
11-50 employees
H1B Sponsorship
Manifold Bio has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2024 (1)
2023 (1)
2021 (1)
Funding
Current Stage
Early StageTotal Funding
$46.4MKey Investors
Amazon Web ServicesTriatomic CapitalPlayground Global
2025-10-08Non Equity Assistance· $1M
2022-06-13Series A· $40M
2020-09-11Seed· $5.4M
Leadership Team
Gleb Kuznetsov
Co-Founder and CEO
Pierce Ogden
Co-Founder & CTO
Recent News
2026-01-11
2025-12-17
Business Wire
2025-12-15
Company data provided by crunchbase