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Pfizer · 4 hours ago

Vice President, Cardiovascular Discovery

Cambridge, MA

Full-time

Hybrid

Director/Executive

$256K/yr - $427K/yr

15+ years exp

Pfizer is focused on developing novel therapies to address key unmet needs in cardiovascular disease. The Vice President, Cardiovascular Discovery will lead a team of researchers to create a portfolio of discovery projects, formulate and implement a cardiometabolic therapeutic strategy, and develop a data-driven research strategy for addressing unmet cardiovascular disease needs.

BiotechnologyHealth CareMedicalPharmaceuticalPrecision Medicine

No H1B

Responsibilities

Apply scientific and clinical expertise to build and implement a strategy for the identification and validation of new drug candidates in the area of cardiovascular disease

As a member of the RU leadership team, contribute to strategic planning and effective operation of the unit

Maintain a ‘cutting edge’ awareness of scientific and technical developments, human genetics, preclinical to clinical translation and apply these where possible to advance the portfolio programs

Design and conduct studies to increase confidence in human biology for new approaches and targets; provide strong scientific leadership and experimental guidance from target generation-to-clinical candidate programs.to a team of scientists with diverse in vitro, ex vivo and in vivo biological expertise

Partner effectively with multi-functional teams encompassing research (including Integrated Biology team and Chemistry) and development (including early and late clinical development group)

Effectively manage and prioritize portfolio of cardiovascular projects ensuring that resources are invested in areas with the highest opportunity for return on investment

Actively contribute to the external collaborative scientific strategy, e.g., identify and build collaborations and liaise with external scientists

Effectively communicate IM’s cardiovascular research to executive leadership as well as external investors and analysts

Serve as a cardiovascular SME in evaluating relevant business development opportunities and develop recommendations to senior leadership on opportunities to pursue or decline

Serve as a cardiovascular SME on the Cardiovascular Safety Council

Create an environment that values innovation, leadership, employee development, scientific excellence, urgency and accountability

Present research findings to the scientific community through consistent publication in peer-reviewed journals and presentation of the results at scientific meetings

Ensure that all research/discovery work is conducted with highest quality and in accordance with relevant regulatory, QC, and compliance guidelines

Provide supervision and career development opportunities for team of 20-25 colleagues

Advise leadership on issues of relative value and prioritization of ongoing programs

Actively explore opportunities for novel investments through partnerships with the outside biotech community and new scientific initiative internally

Qualification

Cardiovascular biologyDrug discovery strategyHuman geneticsNext generation sequencingTranslational biologyBiomarker validationResearch leadershipTeam collaborationCommunication skillsMentoring

Required

MD or PhD with a minimum of 15-20 yrs research experience leading a research laboratory in academic or industry setting, with a sophisticated understanding of modern cardiovascular disease pathophysiology and underlying biology

Proven track record of advancing preclinical cardiovascular discovery programs into clinical development

A demonstrable record of applying the highest scientific rigor and ethical standards to the conduct of biomedical research

Ability to discover, validate and implement novel translation biomarker strategies to support data-driven decisions in clinical development

Demonstrated excellence in designing, executing and interpreting studies of cardiovascular disease biomarkers in nonclinical studies that enable their validation for clinical application

Demonstrated ability to think strategically and creatively while contributing to multiple projects, thrive in a highly collaborative, multi-disciplinary team setting. Strong written/verbal communication skills and ability to effectively collaborate with scientists working in other disciplines are essential

Evidence for prior success in colleague mentoring and career development

Preferred

Demonstrated ability to lead cardiovascular programs through all stages of discovery and clinical development

A demonstrated record of scientific achievement, for example through high quality and impactful publications in leading scientific and/or medical journals