Manager, Clinical Portfolio Services, Business Operations jobs in United States
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Alnylam Pharmaceuticals · 19 hours ago

Manager, Clinical Portfolio Services, Business Operations

Alnylam Pharmaceuticals is seeking a Manager for Clinical Portfolio Services in Business Operations. This role involves financial and resource planning for Clinical Operations, supporting CROs, and ensuring effective financial management processes.

BiotechnologyHealth CareMedicalPharmaceuticalTherapeutics
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Comp. & Benefits
Hiring Manager
Adam Lentz, MBA
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Responsibilities

In partnership with FP&A and Suppliers and Study Management, ensure accurate, transparent, and timely financial analyses to support Clinical Operations accruals; clearly articulate financial implications from variances between forecast and actuals and provide retrospective analysis as well as drive forward actions for key business stakeholders. Supports Clinical Development Expertise Areas as needed
Support Clinical Operations budget, forecast and long-term planning
Complete all required variance analyses for projects. Identify risks in the project forecast and opportunities to improve revenue outlook. Communicate, document and manage these on an ongoing basis
Responsible for review of transparency reporting provided by CRO to ensure alignment with operation plan for study
Develop and deliver training to support effective financial management processes throughout the Clinical Operations organization. Supports Clinical Development Expertise Areas as needed
Manage Purchase Orders (including entry and approval routing) and Change Orders for Clinical Trials
Contribute to continuous improvement and maintain a focus on value-add services relating to resource planning and financial planning

Qualification

Clinical operations knowledgeFinancial analysisProject managementMicrosoft ExcelMicrosoft PowerPointPharma/CRO/Biotech experienceBusiness acumenAnalytical skillsInterpersonal skillsCommunication skillsTeamworkProblem solving

Required

BA/ BS in Operations, Science, Finance or Data Science required
5 years of progressive R&D Business Operations, Sourcing, or Finance/Resourcing roles, with strong analytical and partnering track record
Strong experience in Pharma/CRO/Biotech, specifically with pricing models, supplier contracts and internal budget planning
Strong proficiency in Microsoft Excel (data manipulation) and PowerPoint (leadership presentations)

Preferred

Demonstrated experience with Ariba, SAP, or other financial software

Company

Alnylam Pharmaceuticals

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Alnylam Pharmaceuticals is a biopharmaceutical company focused on the discovery, development and commercialization.

Funding

Current Stage
Public Company
Total Funding
$4.55B
Key Investors
Blackstone Life SciencesBlackstone CreditRegeneron
2025-09-09Post Ipo Debt· $661.25M
2022-09-12Post Ipo Debt· $900M
2022-03-04IPO

Leadership Team

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Yvonne Greenstreet
Chief Executive Officer
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Jeff Poulton
Chief Financial Officer
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Company data provided by crunchbase