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Sampled · 2 months ago

Senior Director Bioinformatics

Piscataway, NJ

Full-time

Onsite

Director/Executive

$180K/yr - $230K/yr

7+ years exp

Sampled is a fully integrated laboratory and biorepository committed to advancing human health through quality sample storage and analysis services. The Senior Director of Bioinformatics will lead a multidisciplinary team to develop computational biology capabilities and support genomic research, focusing on NGS data analysis and bioinformatics tool development.

Health CareInformation Technology

Responsibilities

Lead and develop the core bioinformatics team(s) and serve as a mentor for other bioinformatics and/or software developer staff members on analysis approaches and best practices

Leverage leadership skills and experiences to continuously improve the function, including talent, structure, processes, tools, and techniques

Lead and execute product strategy and service roadmap

Lead and manage internal challenges / conflicts at enterprise scale and complexity, working in partnership and collaborating with lab services

Successfully and closely collaborate with clients and program managers in leading the design, implementation and refinement of the tools, methods and pipelines

Work with research and development teams to participate in project planning and design plan for bioinformatics development, execution, and test/validation

Ensure products meet regulated and/or clinical validated products requirements; for example, GxP, CLIA or CAP environments

Ensure all change controls follow quality control software development best practice, SOPs and regulatory requirements

Daily focus of self on bioinformatics tool development needs of NGS pipeline, microarray data analysis and process automation

Analyze R&D data for assay development and other research needs

Perform tool validation and generate validation reports

Troubleshooting of bioinformatics tool issues

Provide support for daily data analysis and data delivery

Evaluate third party bioinformatic tools, perform proof-of-concept test, and provide adoption and integration strategy

Develop new solutions including data analysis pipeline using Python, Nextflow and WDL

Working with IT, develop and implement data storage and backup plan and support company growth

Be a proactive member of Sampled’s Global Senior Leadership Team (SLT), maximizing internal communication and team work opportunities, and ensuring personal accountability and ownership to deliver on commitments

Build a positive culture, and be an active champion and role model of Sampled Core Values: Strive to delight our clients, Move innovation forward, Accelerate your business, Rise together as a team, Transcend what is possible

Qualification

Bioinformatics team leadershipNGS pipeline designGenomicsProteomicsMachine learning applicationsAWS EngineeringHPCLinuxPython programmingDatabase designStakeholder managementProject managementCommunication skillsOrganizational skills

Required

Ph.D. degree in Bioinformatics, Computational Biology, Engineering, Computer Science, and other related fields with minimal five years biotech and/or pharmaceutical experiences or Master's degree minimal eight years biotech and or pharmaceutical experiences

7+ years experience leading Bioinformatics teams at Director level or above, including managing remote based team members

Excellent leadership skills and the ability to set direction and develop the team

Strategic mindset and high business acumen

High level of project management and cross-functional collaboration skills, with the ability to build relationships and trust across the organization

Ability to drive change and engagement

Demonstrates consistently good communication and interpersonal skills with colleagues, management and clients

Strong stakeholder management skills internally and externally, with ability to build relationships, resolve conflict, navigate through challenges and influence outcomes

A minimum of 3 years CLIA lab experience for genetic testing

Scientific experiences in genomics, proteomics, and precision medicine with proof of publications

Expert experiences in NGS pipelines design and development for germline and cancer variant detections with DNA and RNA panel, WES and WGS

Liquid biopsy and metagenomic bioinformatics pipeline development experiences

Applied machine learning and other AI technology in large scale of biological data analysis

Strong organization skills, with attention to priorities, effectively meeting deadlines and responding in a timely manner

Ability to prioritize tasks and to delegate them when appropriate

Able to be site based in Piscataway, New Jersey, minimum 3 days per week

Preferred

AWS Engineering: 4 years

HPC and Linux: 8 years

Python Programing: 8+ years

Web Development: 3+ years

Strong Python programming skills including experiences with Pandas, Numpy, and machine learning functions

PostgreSQL and MySQL databases, data modeling and database design, data ETL (Extraction, Transformation, and Loading) skills, SQL, and other data and database skills

Good software development practices, including code management using Git, JIRA, Confluence

Experiences with workflow management tools such as Snakemake, Nextflow and WDL (Workflow Description Language)