Amgen · 1 month ago
Senior Engineer: Mathematical Modeling and Simulation
US - Massachusetts - Cambridge
Full-time
Hybrid
Mid, Senior Level
$119K/yr - $148K/yr
4+ years expAmgen is a biotechnology company focused on serving patients living with serious illnesses. The Senior Engineer in Mathematical Modeling and Simulation will develop and deploy advanced simulation technologies to improve process understanding and optimize manufacturing of combination products.
BiotechnologyHealth CareManufacturingPharmaceutical
Responsibilities
Implementing explicit and implicit FEM structural models. Ensuring that the approach and simplifications used to build these models is efficiently representing the physical system
Applying engineering principles like kinematic, structural, and tolerance analysis combined with material characterization and testing to create in-silico models able to capture the behavior of the device during use, assembly and transport
Continuous improvement of in-silico models, managing the lifecycle of the model and improving methods and workstreams to guarantee efficiency and trustworthiness of the models
Demonstrating critical and analytical thinking skills to explore new opportunities in in-silico and data-driven computational models. Modeling real-world scenarios with the adequate level of detail and help inform the decision making in a reduced time frame
Simulate complaints and real-world issues within lifecycle of combination products. Being able to apply an analytical approach to create models that accurately represent the real world scenarios and helps identify the root cause analysis of any complaint
Providing positive leadership and delivering work in a fast-paced, multi-project, cross-functional environment. Delivering predictions and insight on time to solve challenging production and customer problems
Model ownership, responsible for developing and managing backlog of in-silico product projects. Being able to concisely communicate on the modelling scope, limitations and assumptions to stakeholders with a technical and not technical background. Mentor also other simulation experts in the best use of simulation technologies
Qualification
Required
Doctorate degree
OR Master's degree and 2 years of Engineering experience
OR Bachelor's degree and 4 years of Engineering experience
OR Associate's degree and 8 years of Engineering experience
OR High school diploma / GED and 10 years of Engineering experience
Preferred
Finite element model experience with a commercial platform like SIMULIA, ANSYS, ALTAIR or COMSOL
Experience in explicit FEM modelling and non-linear structural models; contact modelling, large deformations, plasticity, and hyperelasticity
Knowledge of statistic and robustness analysis principles, being able to create models capturing the inherent variability in the process and device dimensions
Skilled in programming in Python, and/or MATLAB for engineering purposes. Scripting using commercial software codes like abaqus user subroutines, Tcl/Tk to automate model creation and post/processing
Experience with combination products and device regulatory requirements, medical device development and design controls, and knowledge of process controls
Excellent communication, presentation, and technical documentation skills are highly desired
Intellectual curiosity with ability to learn new concepts/frameworks, algorithms, and technology rapidly as needs arise
Ability to manage multiple competing priorities simultaneously and work in highly collaborative, cross-functional environments
Benefits
A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
Stock-based long-term incentives
Award-winning time-off plans
Flexible work models where possible.
Company
Amgen
Amgen is a biotechnology company that develops and manufactures human therapeutics for various illnesses and diseases.
10001+ employees
H1B Sponsorship
Amgen has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (429)
2024 (485)
2023 (485)
2022 (540)
2021 (460)
2020 (444)
Funding
Current Stage
Public CompanyTotal Funding
$28.5B2022-12-12Post Ipo Debt· $28.5B
1983-06-17IPO
Leadership Team
Robert Bradway
Chairman and Chief Executive Officer
Jay Bradner
Executive Vice President of R&D, and Chief Scientific Officer
Recent News
Genetic Engineering News
2026-01-12
2026-01-11
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