SRT Therapeutics Inc. · 1 month ago
Sr. Scientist, Biomarkers
San Diego, CA
Full-time
Onsite
Mid, Senior Level
$120K/yr - $160K/yr
5+ years expSRT Therapeutics is a San Diego-based biotech company focused on enhancing patient outcomes through precision medicine approaches. They are seeking a highly motivated Senior Scientist to join their Predictive and Translational Biomarkers team, responsible for designing and executing complex experiments and developing translational biomarker assays to support IND-enabling work.
BiopharmaBiotechnologyHealth CareWellness
Responsibilities
Design, develop, and execute complex primary functional assays to assess drug mechanism of action (MoA) and advance our multi-omic strategy for predictive biomarker discovery
Design, optimize, and validate high parameter immunophenotyping panels for immune cell characterization from patient samples
Develop translational biomarker assays including target engagement, receptor occupancy, and pharmacodynamic endpoints to support IND-enabling studies and early clinical development
Perform high-quality data analysis, interpretation, and rigorous documentation of experimental results in ELNs and technical reports
Contribute scientifically to project team discussions by providing insight and proposing clear, feasible, and robust laboratory experimental plans to address major questions
Collaborate closely with the Computational Biology and Biobanking groups by ensuring that generated data is standardized, of high quality, and organized appropriately to support predictive biomarker discovery
Qualification
Required
PhD or equivalent experience in Immunology, Cell Biology, or a closely related field with 5+ years of industry or mixed academic/industry experience in immunology, drug discovery, or translational research
Extensive hands-on expertise in immunology lab techniques, including demonstrated ability to isolate, culture, and characterize primary human immune cells and tissue
Deep technical proficiency in advanced multi-color flow cytometry (panel design, optimization, acquisition, and analysis using software such as FlowJo)
Demonstrated experience in primary cell functional assay development relevant to inflammatory/autoimmune disease
Prior experience in the development or technical execution of assays for translational biomarkers (e.g., pharmacodynamic endpoints, target engagement, receptor occupancy)
Proven ability to work independently and efficiently in a laboratory setting, manage time effectively, and troubleshoot complex technical issues
Strong communication skills, with the ability to clearly present detailed laboratory findings and proposed next steps to a scientific team
Benefits
Health, dental, and vision insurance
Paid time off and company holidays
Bonus & Equity eligibility
Company
SRT Therapeutics Inc.
SRT Therapeutics is a San Diego-based biotech company established in 2024 by the founders of Prometheus Biosciences, Steph Targan, MD (Cedars Sinai), Janine Bilsborough, Ph.D.
11-50 employees
Funding
Current Stage
Early StageTotal Funding
$47.4M2025-08-13Undisclosed· $47.4M
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