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ImmunoVec · 1 month ago

Scientist / Senior Scientist - Non-Viral Gene Delivery

Los Angeles, CA

Full-time

Onsite

Mid, Senior Level

3+ years exp

ImmunoVec is a biotechnology company pioneering in vivo cell engineering through non-viral DNA delivery. The Scientist / Senior Scientist will drive the design and optimization of polymer, lipid nanoparticle, and electroporation-based delivery systems for primary human immune cells, leading efforts in screening novel constructs and evaluating efficacy using in vivo models.

BiotechnologyGeneticsHealth CareMedical

H1B Sponsor Likely

Responsibilities

Design, plan, and execute innovative high-throughput screens to evaluate and optimize non-viral gene delivery in primary human immune cells using PNPs, LNPs and electroporation-based systems

Design, synthesize and formulate novel PNPs and LNPs

Functionalize novel non-viral delivery vehicles with targeting ligands

Develop and refine functional assays to assess delivery efficiency, transgene expression, cytokine production, and immune cell activation or suppression

Lead 1-2 Research Associates, ensuring high-quality experimental design and clear documentation

Support in vivo studies by coordinating formulation testing, immune monitoring, and biodistribution analysis in preclinical mouse models

Stay at the forefront of the field by tracking emerging literature, tools, and technologies in non-viral gene delivery, nanomedicine, and immune cell engineering

Qualification

Non-viral delivery systemsLipid Nanoparticle (LNP) formulationPolymer Nanoparticle (PNP) transfectionFlow cytometryCytokine profilingMurine tumor modelsData interpretationStatistical analysisCAR-T cell biologyCAR-NK cell biologyImmune cell phenotypingHigh-throughput screening

Required

Ph.D. in Biomolecular Engineering, Immunology, Cell Biology, Nanoparticle Chemistry or a related field (Scientist), with at least 3 years of postdoc or industry experience (Sr Scientist)

Hands-on experience with designing, synthesizing, formulating, and evaluating non-viral delivery vehicles, such as LNPs or PNPs is essential

Demonstrated expertise in CAR-T or CAR-NK cell biology, including functional characterization, activation assays, and immune cell phenotyping

Proficiency in data interpretation and statistical analysis, with working knowledge of tools such as FlowJo, GraphPad Prism, and related analytics software

Preferred

Familiarity with preclinical mouse models relevant to immuno-oncology (such as syngeneic tumor models or humanized xenografts) is advantageous

Benefits

Full health, dental and vision insurance

Matching 401K

Company

ImmunoVec

ImmunoVec develops gene therapy treatments to cure terminal genetic diseases of the immune system.

Founded in 2019

Santa Monica, California, USA

2-10 employees

https://www.immunovec.com/

H1B Sponsorship

ImmunoVec has a track record of offering H1B sponsorships. Please note that this does not guarantee sponsorship for this specific role. Below presents additional info for your reference. (Data Powered by US Department of Labor)

Distribution of Different Job Fields Receiving Sponsorship

Represents job field similar to this job

Trends of Total Sponsorships

2023 (3)

Funding

Current Stage

Early Stage

Total Funding

$45M

Key Investors

Advanced Research Projects Agency for Health

2025-09-22Grant· $40.7M

2022-03-01Seed· $4.3M

Leadership Team

Ryan Wong

Chief Executive Officer

Recent News

Pulse 2.0

ImmunoVec: $40.7 Million Raised From ARPA-H To Improve In Vivo Cell Engineering for Autoimmune Diseases

2025-10-16

FierceBiotech

US government pumps money toward in vivo cell therapy programs

2025-10-14

PR Newswire

ImmunoVec Launches from Stealth with up to $40.7 Million ARPA-H EMBODY Award to Advance In Vivo Cell Engineering Platform for Autoimmune Diseases

2025-10-09

Company data provided by crunchbase