Amgen · 1 month ago
Scientist - LC-MS Bioanalytical
Thousand Oaks, CA
Full-time
Hybrid
Mid, Senior Level
3+ years expAmgen is a biotechnology company dedicated to serving patients with serious illnesses. The Scientist - LC-MS Bioanalytical will support the design, development, validation, and implementation of bioanalytical methods for various therapeutic modalities, ensuring compliance with regulatory expectations and contributing to scientific publications.
BiotechnologyHealth CareManufacturingPharmaceutical
Responsibilities
Perform quantitative bioanalytical experiments and organize data and results, including planning and running LC-MS/MS bioanalysis and preparing and analyzing biological samples
Develop and implement LC-MS/MS bioanalytical methods with quick turnaround times
Conduct small and large molecule bioanalysis in non-clinical and clinical samples from various matrices (plasma, urine, CSF, tissues)
Perform biological sample extraction using protein crash (PPT), SPE, LLE, and/or affinity capture methodologies
Generate complete, accurate, and concise documentation using electronic systems and laboratory notebook
Ensure bioanalytical data meets regulatory expectations for global submissions by maintaining accurate records and staying current with industry guidelines
Author study reports, standard operating procedures, analytical methods, memos, and other regulatory-compliant documents
Communicate bioanalytical data to key discovery and development teams, contribute to scientific publications, and present at professional meetings
Comply with safety guidelines and site-specific procedures which include but is not limited to the completion of training on assigned tasks, maintenance of training records, laboratory documentation, and following detailed SOPs and other written procedures
Perform general laboratory housekeeping activities and operational support as needed, including QC of reports
Qualification
Required
Doctorate degree PhD or PharmD or MD [and relevant post-doc where applicable] and 1-3 years of relevant industrial or postdoctoral experience
Master's degree and 5 years of relevant industrial/technical experience
Bachelor's degree and 7 years of relevant industrial/technical experience
Preferred
Prior experience in CRO or pharma/biotech strongly desired
Strong technical expertise in quantitative mass spectrometry on triple quadrupole (QQQ) platforms as well as HRMS
Experience with an array of analytical technologies that can accelerate bioanalysis inclusive of automation and/or micro-sampling
Prior GLP and GCP experience
Demonstrated expertise in working with a variety of sample types (e.g., blood, plasma, serum, tissues, cerebrospinal fluid) and employing diverse sample preparation techniques (e.g., SPE, LLE, immunocapture) to support analysis of different therapeutic modalities, including small and large molecules by LC-MS
Prior experience in bioanalytical (regulated) assay execution and transfer to CROs
Must be willing to work in a fast-paced, multi-project environment with high workload demands, and consistently deliver high-quality results within established timelines
Demonstrated ability to resolve scientific challenges efficiently and prioritize effectively
Excellent scientific problem-solving skills
Excellent project and time management abilities
Ability to work collaboratively with internal and external stakeholders
Supervisory and mentoring experience in a lab-based setting
Benefits
A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
Stock-based long-term incentives
Award-winning time-off plans
Flexible work models, including remote and hybrid work arrangements, where possible
Company
Amgen
Amgen is a biotechnology company that develops and manufactures human therapeutics for various illnesses and diseases.
10001+ employees
H1B Sponsorship
Amgen has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (429)
2024 (485)
2023 (485)
2022 (540)
2021 (460)
2020 (444)
Funding
Current Stage
Public CompanyTotal Funding
$28.5B2022-12-12Post Ipo Debt· $28.5B
1983-06-17IPO
Leadership Team
Robert Bradway
Chairman and Chief Executive Officer
Jay Bradner
Executive Vice President of R&D, and Chief Scientific Officer
Recent News
2026-01-24
2026-01-22
Company data provided by crunchbase