Colossal Biosciences · 4 weeks ago
Senior Research Associate, Stem Cell Engineering
Dallas, TX
Full-time
Onsite
Senior LevelColossal Biosciences is seeking a skilled and motivated stem cell engineer to support efforts in engineering embryonic and pluripotent cell systems for non-model species. The Senior Research Associate will contribute to experimental planning, execution, and documentation, playing a key role in advancing foundational stem cell platforms for cellular engineering and translational biology across marsupial species.
BiotechnologyGeneticsLife Science
Responsibilities
Contribute to the design, development, and execution of novel experiments, techniques, and protocols under the guidance of scientists, with growing autonomy in protocol optimization and troubleshooting
Perform and support 2D and 3D cell culture of primary, immortalized, ESC, and iPSC lines with high technical accuracy
Conduct and troubleshoot FACS, Western blotting, qPCR, immunostaining, transfection, and microscopy-based assays
Support stem cell reprogramming workflows, including those for non-model species, with adaptability and a willingness to learn species-specific protocols
Maintain and optimize 3D culture systems, including spheroid and organoid models
Characterize and perform quality control of marsupial stem cell cultures, with training provided where needed
Document experimental work thoroughly and contribute to reports, presentations, and publications
Maintain accurate, up-to-date digital lab records and follow team SOPs and quality standards
Support live cell maintenance, including occasional weekend work depending on feeding or culture requirements
Qualification
Required
Experience working with primary embryonic and iPSC cultures, including maintenance and expansion techniques
Proficiency in core molecular biology techniques, including qPCR, immunohistochemistry, colony picking, and stem cell passaging workflows
Familiarity with stem cell reprogramming technologies, particularly iPSC generation and validation
Experience using electronic lab notebooks (ELNs) and inventory management systems (e.g., Benchling) for data tracking and reagent management
Bachelor's or Master's degree in biological sciences, molecular and cell biology, bioengineering, biochemistry, developmental biology, or a related field
Prior experience as a Research Associate or Technician in an academic or biotechnology industry setting is a plus
Preferred
Experience with RNA extraction, RNA handling, and protein quantification assays (e.g., ELISA and Western blot)
Experience with cell line derivation, propagation, and transfection methodologies, especially when following established protocols
Familiarity with sequence analysis software such as SnapGene or Geneious
Experience with non-model systems or comparative biology is welcomed but not required
Benefits
Medical, dental, and vision coverage
Excellent paid time off and company holidays so you can rest and recharge
Flexible spending accounts (FSA)
Company matched 401k retirement plan
Paid parental leave at 100% salary for up to 12 weeks
Education reimbursement
Company
Colossal Biosciences
Colossal Biosciences is a biotechnology and genetic engineering company that uses gene editing technology to de-extinct species.
Founded in 2021
51-200 employees
H1B Sponsorship
Colossal Biosciences has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (1)
2024 (6)
2022 (4)
Funding
Current Stage
Growth StageTotal Funding
$568.1MKey Investors
US Innovative Technology FundIQTThomas Tull
2025-09-17Series C· $120M
2025-01-15Series C· $200M
2023-11-13Series Unknown· $10.5M
Leadership Team
Ben Lamm
Founder and CEO
Brian Beard
Co-Founder, Chief Global Strategy and Legal Officer and Board Member
Recent News
Business Standard India
2025-12-25
2025-12-17
Company data provided by crunchbase