Ionis Pharmaceuticals, Inc. · 2 days ago
Computational Biology Post Doctorate Fellow, Biomarker Department
Carlsbad, CA
Full-time
Hybrid
New Grad, Entry Level
$65K/yr - $87K/yrIonis Pharmaceuticals, Inc. is a pioneer in RNA-targeted medicines, seeking a highly motivated Postdoctoral Fellow in their Biomarker group. The role involves developing and implementing biomarker strategies, analyzing proteomic and EEG data, and collaborating with external partners to support neurology programs.
BiotechnologyHealth CareMedicalPharmaceutical
Responsibilities
Responsible for working with collaborators and within the Biomarker group to access, harmonize, and analyze various proteomics data as well as EEG data
Independently design and deploy computational pipelines to process and analyze proteomics and EEG data
Communicate in an effective and timely manner with team members regarding project status, timelines, and analysis updates
Integrate findings from omics datasets to support Ionis programs
Participate in Ionis collaborations to access and contribute to additional datasets for application to related projects
Qualification
Required
Bioinformatician with PhD in computational biology or related field
Critical-thinking and problem-solving skills with attention to detail
Experience devising, designing, and executing scientific experiments and projects
Expected experience includes working with multi-modal omics datasets and large proteomic datasets (O-link, untargeted LC-MS data, etc), evidenced by high-impact publications
Applicants should be proficient in R, Python or another appropriate programming language for analysis of processed proteomics data (e.g. SomaScan, label-free or TMT mass spectrometry), including data wrangling, QC, normalization, and differential protein abundance testing
Experience with packages such as tidyverse, MSstats, DEP2, pandas, numpy, and scikit-learn, as well as pathway and network analysis tools (e.g. GSEA/fgsea, clusterProfiler), is highly desirable
Ability to multi-task and manage several projects in parallel
Work collaboratively and productively in fast-paced cross-functional teams
Excellent communicator who is comfortable presenting in cross-functional meetings and maintaining open and effective lines of dialogue, addressing problems and collaborating constructively with team members
Must be organized, adaptive, and detail oriented, with the ability to multitask, and manage multiple tasks in parallel with competing priorities
Proven ability of being productive and successful in an intense work environment
Candidate must be in San Diego or willing to relocate (fully onsite or hybrid)
Travel minimal 0-10%
Preferred
Degree and/or background working on neurological diseases and/or biomarker discovery would be a plus
Experience handling EEG data is not required
The following experience would be beneficial but is not essential: Running assays such as targeted protein ELISAs to validate computational findings
Benefits
Ionis offers an excellent benefits package!
Company
Ionis Pharmaceuticals, Inc.
For three decades, Ionis has invented medicines that bring better futures to people with serious diseases.
Founded in 1989
501-1000 employees
H1B Sponsorship
Ionis Pharmaceuticals, Inc. has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (8)
2024 (5)
2023 (3)
2022 (5)
2021 (5)
2020 (1)
Funding
Current Stage
Public CompanyTotal Funding
$2.45B2025-11-13Post Ipo Debt· $700M
2024-09-09Post Ipo Equity· $500.3M
2023-06-06Post Ipo Debt· $500M
Leadership Team
Brett P. Monia
Chief Executive Officer
Eric Bastings
Senior Vice President, Development Strategy
Recent News
2025-12-11
Company data provided by crunchbase