Pharmacology Research Scientist jobs in United States
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Vertex Pharmaceuticals · 2 days ago

Pharmacology Research Scientist

Vertex Pharmaceuticals is a global biotechnology company that invests in scientific innovation. They are seeking a talented in-vivo pharmacologist to support late-stage drug discovery by designing, executing, and interpreting in vivo/ex vivo experiments to establish therapeutic proof-of-concept across diverse disease areas.

BiotechnologyHealth CareMedicalPharmaceutical
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Growth Opportunities
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H1B Sponsor Likelynote

Responsibilities

Designs and conducts elaborate, conceptually connected, multi-component in vivo/ex vivo experiments to demonstrate proof-of-concept in preclinical disease models including pharmacokinetic, pharmacodynamic and efficacy relationships
Perform advanced and/or complex experimental assay development and troubleshooting
Collates and interprets complex data systematically and synthesizes results into a cohesive body of conclusions or recommendations to guide Project decisions and new research activities
Exercises solid judgment to prioritize studies, considering feasibility and Project impact
Scours relevant scientific literature and routinely incorporates new insights into research activities
Identifies, prioritizes and introduces relevant emerging technologies in their field of expertise to advance the existing technology platforms and create/maintain a competitive advantage
Explores the feasibility of applying new scientific principles/concepts or implements and validates novel experimental approaches and technologies to achieve project goals
Contributes significantly to patent and/or publication preparation
Independently prepares study presentations and presents experimental conclusions at internal Group/Department or Project Team research meetings
Performs other duties as assigned

Qualification

Vivo pharmacologyExperimental assay developmentData interpretationRodent handlingPharmacology principlesAssay troubleshootingMolecular techniquesCommunication skillsTeam collaborationAdaptability

Required

Bachelor's degree in pharmacology or related biological sciences
Typically requires a PhD and 0-3 years of experience or
Typically requires a Masters degree and 3 years of experience or
Typically requires a Bachelors degree and 6 years of experience
Proficient in rodent handling, dosing (IV, PO, IP, SC), blood collection (tail nick, submandibular, cardiac puncture) and tissue harvesting
Experience developing, executing and troubleshooting assays across a wide array of in vivo and molecular techniques (i.e. ELISA, qPCR, Western and flow cytometry)
Ability to rapidly learn and master new techniques and technologies
Integrity, flexibility, adaptability, organization and multi-tasking skills, excellent record keeping and the ability to function both independently and effectively as part of an interactive and cross-functional team
Designs and conducts elaborate, conceptually connected, multi-component in vivo/ex vivo experiments to demonstrate proof-of-concept in preclinical disease models including pharmacokinetic, pharmacodynamic and efficacy relationships
Perform advanced and/or complex experimental assay development and troubleshooting
Collates and interprets complex data systematically and synthesizes results into a cohesive body of conclusions or recommendations to guide Project decisions and new research activities
Exercises solid judgment to prioritize studies, considering feasibility and Project impact
Scours relevant scientific literature and routinely incorporates new insights into research activities
Identifies, prioritizes and introduces relevant emerging technologies in their field of expertise to advance the existing technology platforms and create/maintain a competitive advantage
Explores the feasibility of applying new scientific principles/concepts or implements and validates novel experimental approaches and technologies to achieve project goals
Contributes significantly to patent and/or publication preparation
Independently prepares study presentations and presents experimental conclusions at internal Group/Department or Project Team research meetings
Designs and executes complex, well controlled, challenging experiments that measure the action of compounds on in vivo/ex vivo disease biology assays
Maintains a broad working knowledge of fundamental pharmacology principles
Demonstrates astute understanding of his/her own discipline and the relevant literature
Maintains a high level of knowledge related to current developments in the scientific Project field
Displays proven productivity and experimental creativity, and effective dissemination of ideas
Demonstrates effective, self-sufficient communication skills, especially in peer-directed presentations
Demonstrates awareness of other Project-related disciplines and an understanding of general concepts and some experimental detail within those areas

Benefits

Annual bonus
Annual equity awards
Overtime pay
Medical benefits
Dental benefits
Vision benefits
Generous paid time off
Educational assistance programs
Student loan repayment
Generous commuting subsidy
Matching charitable donations
401(k)

Company

Vertex Pharmaceuticals

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Vertex Pharmaceuticals is focused on the discovery and development of small molecule drugs for the treatment of serious diseases.

H1B Sponsorship

Vertex Pharmaceuticals has a track record of offering H1B sponsorships. Please note that this does not guarantee sponsorship for this specific role. Below presents additional info for your reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (188)
2024 (150)
2023 (111)
2022 (164)
2021 (112)
2020 (80)

Funding

Current Stage
Public Company
Total Funding
$657.31M
Key Investors
Janssen Belgium
2024-07-10Post Ipo Secondary· $1.11M
2022-05-17Post Ipo Equity· $50M
2009-12-03Post Ipo Equity· $443M

Leadership Team

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Reshma Kewalramani
CEO and President
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Nina Devlin
Senior Vice President, Chief Communications Officer
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Company data provided by crunchbase