Korro Bio, Inc. · 3 days ago
Senior Scientist, Analytical Sciences
Cambridge, MA
Full-time
Onsite
Senior Level
$140K/yr - $187K/yr
7+ years expKorro Bio, Inc. is a biopharmaceutical company focused on developing innovative genetic medicines. The Senior Scientist in Analytical Sciences will manage CMO analytical labs, develop analytical methods, and ensure the quality and stability of RNA-based therapies throughout the development lifecycle.
BiotechnologyHealth CarePharmaceutical
Responsibilities
Serve as SME for RNA-based drug substance and drug product release and characterization assays including assay develop and optimize analytical methods as needed
Support analytical method validation, transfer, and troubleshooting to ensure compliance with cGMP standards
Collaborate with the Process Development teams to ensure seamless integration of analytical methods into DS and DP manufacturing workflows
Analyze, interpret, and present complex data to cross-functional teams and senior management
Author and review technical reports, protocols, SOPs, and sections of regulatory filings (IND, IMPD etc.)
Assist in managing external analytical collaborations with CROs and CMOs, ensuring data quality and timelines are met
Stay current with emerging analytical technologies and apply innovative solutions to improve method robustness and efficiency
Support investigations and root cause analyses for any out-of-specification (OOS) results, deviations, or process failures
Qualification
Required
PhD in Analytical Chemistry, Biochemistry, Molecular Biology, or related field with 2+ years' experience; or MS with 7+ years or BS with 9+ years of relevant industry experience
3+ years of hands-on experience in analytical method development for biologics, with experience in RNA therapeutics preferred
Expertise in chromatographic (e.g., UPLC -UV, and UPLC-MS) and spectroscopic techniques (e.g., UV-Vis), with a strong understanding of method validation requirements
Familiarity with cGMP and ICH guidelines for analytical development and quality control of small molecules and/or biologics
Experience with supporting design and management of stability studies, impurity profiling, and degradation pathways
Expertise with managing primary and working reference standard qualification, aliquoting, and long-term management across all end users of the material
Managed transfer, qualification, and ideally validation of methods
Supported batch disposition, OOS, OOT, and investigations
Excellent written and verbal communication skills, with experience drafting technical reports and regulatory documents
Ability to work collaboratively in a fast-paced environment and manage multiple projects simultaneously
Preferred
Experience in RNA therapeutics
Benefits
Competitive compensation
Equity-based compensation
Medical
Dental
Vision
401(k) retirement plan
Life insurance
A dependent care flexible spending account
Company-funded health savings account
Free parking
Company
Korro Bio, Inc.
Korro Bio was founded to turn extraordinary scientific insights into life-altering new treatments for patients.
51-200 employees
H1B Sponsorship
Korro Bio, Inc. has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (2)
2022 (1)
Funding
Current Stage
Public CompanyTotal Funding
$277.5MKey Investors
Deep Track CapitalEventideWu Capital
2024-04-18Post Ipo Equity· $70M
2023-11-06IPO
2022-01-05Series B· $116M
Leadership Team
Ram Aiyar
Chief Executive Officer
Todd Chappell
Chief Operating Officer
Recent News
New Enterprise Associates
2026-01-05
Genetic Engineering News
2025-11-19
Company data provided by crunchbase