Senior Research Associate II, Medicinal Chemistry jobs in United States
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Maze Therapeutics · 9 hours ago

Senior Research Associate II, Medicinal Chemistry

positionSouth San Francisco, CA
timeFull-time
remoteOnsite
seniorityMid, Senior Level
money$120K/yr - $147K/yr
date4+ years exp

Maze Therapeutics is a clinical-stage biopharmaceutical company focused on developing novel small molecule precision medicines. The Senior Research Associate II will apply expertise in organic and medicinal chemistry to synthesize, purify, and characterize novel molecules, collaborating across functions to advance research programs.

BiopharmaBiotechnologyGeneticsTherapeutics
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H1B Sponsor Likelynote

Responsibilities

Execute multistep syntheses of complex small molecules and characterize intermediates and final products
Propose new compounds for synthesis based on SAR and synthetic knowledge
Summarize and interpret results and present findings in research meetings
Learn new laboratory techniques, troubleshoot experiments, and ensure high-quality execution
Utilize scientific literature and databases (e.g., SciFinder) to design efficient synthetic routes
Collaborate with scientists across functions to develop and optimize newly generated molecules

Qualification

Organic synthesisChromatographic purificationCompound characterizationAnalytical techniquesScientific literature utilizationOrganizational skillsCollaborationCommunication skillsAdaptability

Required

B.S./M.S. in Chemistry with at least 4 years of relevant experience in synthetic organic or medicinal chemistry
Demonstrated experience in organic synthesis, chromatographic purification, and compound characterization using modern analytical techniques (NMR, LCMS, HPLC, etc.)
Strong organizational skills and attention to detail
A proactive, solution-oriented approach and commitment to collaboration
Ability to learn and adapt in a fast-paced environment
Excellent verbal and written communication skills

Benefits

Competitive medical, dental, and vision insurance
Mental health offerings
Equity incentive plan
401(k) program with employer match
Generous holiday and PTO policy

Company

Maze Therapeutics

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Maze Therapeutics is a biotechnology company that develops precision medicines for renal, cardiovascular, and metabolic diseases.
dateFounded in 2017
location
South San Francisco, California, USA
people-size51-200 employees
web-link
https://www.mazetx.com

H1B Sponsorship

Maze Therapeutics has a track record of offering H1B sponsorships. Please note that this does not guarantee sponsorship for this specific role. Below presents additional info for your reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (2)
2024 (3)
2023 (2)
2022 (5)
2021 (3)
2020 (1)

Funding

Current Stage
Public Company
Total Funding
$646M
Key Investors
Matrix Capital ManagementCity Hill Ventures
2025-09-11Post Ipo Equity· $150M
2025-01-31IPO
2024-12-03Series D· $115M

Leadership Team

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Jason Coloma
Chief Executive Officer
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Misbah Tahir
Chief Financial Officer
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Recent News

General Catalyst
General Catalyst Portfolio
2026-01-13
BioSpace
IPOs Slow to a Trickle in 2025 as Investors Grow More Discerning
2026-01-06
Maze Therapeutics, Inc.
Maze Therapeutics Reports Third Quarter 2025 Financial Results and Recent Highlights
2025-11-09
Company data provided by crunchbase