Syneos Health · 4 weeks ago
Principal Clinical Data Scientist- Data Management
United States
Full-time
Remote
Lead/Staff
$95K/yr - $176K/yr
10+ years expSyneos Health® is a leading fully integrated biopharmaceutical solutions organization built to accelerate customer success. The Principal Clinical Data Scientist provides strategic and operational leadership for end-to-end clinical data collection, cleaning, and quality oversight across complex clinical studies, ensuring deliverables are compliant and aligned with sponsor expectations.
BiotechnologyHealth CarePharmaceuticalTherapeutics
Responsibilities
Serve as the Data Management Functional Lead for Clinical Data Science on complex, multi-scope clinical projects and act as the primary liaison between Clinical Data Science, Project Management, Clinical Monitoring, and other functional groups.
Develop Data Management Plan, Communicate, troubleshoot, and resolve complex data-related issues; recommend solutions and escalate issues impacting patient safety, data integrity, or study analysis
Act as the central steward of clinical data quality through holistic review of clinical and operational data using detailed protocol and therapeutic area knowledge
Ensure required data elements and corresponding data quality oversight steps are identified to support defined study analyses
Coordinate cross-functional data cleaning activities to meet quality standards, timelines, and contractual obligations
Communicate, troubleshoot, and resolve complex data-related issues; recommend solutions and escalate issues impacting patient safety, data integrity, or study analysis
Develop Clinical Data Acquisition Plans and data flow diagrams for complex studies and align data flow with study protocols, regulatory requirements, and study endpoints
Assess risks related to protocol design, program-level strategies, and study parameters that may impact data credibility and trial reliability
Design and drive development of analytical tools and dashboards to identify potentially unreliable or high-risk data
Perform analytic reviews as defined in the scope of work and data acquisition plans; identify root causes and implement systematic resolutions
Demonstrate understanding of advanced technologies and assess their applicability to individual studies or programs
Monitor and communicate project progress using status reports, tracking tools, and metrics to Sponsors and internal teams
Ensure launch, delivery, and completion of Clinical Data Science milestones in compliance with contracts, SOPs, guidelines, and regulatory requirements
Collect and analyze metrics to support continuous process improvement initiatives
Review and manage Clinical Data Science budgets, identify out-of-scope activities, and initiate change orders through Project Management
Plan, manage, and allocate Clinical Data Science resources and coordinate the work of assigned team members
Develop and maintain project plans, specifications, and documentation in compliance with SOP requirements
Maintain ongoing documentation and ensure Trial Master File (TMF) completeness and accuracy
Participate in and present at internal, Sponsor, investigator, and third-party meetings
Provide input to proposals, bid defenses, and RFP responses and promote new Clinical Data Science business opportunities aligned with Sponsor strategies
Prepare documentation for and participate in internal and external audits
Train and mentor junior team members and maintain proficiency in Clinical Data Science systems through ongoing training
Perform other duties as assigned
Qualification
Required
Bachelor's degree in Biological Sciences, Computer Science, Mathematics, Data Science, or related discipline required
Minimum of 10 years of experience in Clinical Data Management and/or Clinical Data Science
At least 5 years of project management experience
Experience with Clinical Data Science practices and relational database management systems
In-depth knowledge of the drug development lifecycle, including risk-based data quality approaches and biometrics workflows
Expertise in protocol interpretation, data collection strategies, and data cleaning specification development
Knowledge of ALCOA++ data quality principles
Knowledge of medical terminology, clinical trial data, and ICH/GCP regulatory requirements
Proficiency with Microsoft Word, Excel, PowerPoint, email, and Windows-based applications
Strong leadership, communication, organizational, and time-management skills
Ability to manage multiple priorities in a fast-paced, dynamic environment
Ability to work independently and collaboratively across multidisciplinary teams
Preferred
Master's degree preferred
Equivalent relevant experience may be considered in lieu of degree
Benefits
Company car or car allowance
Health benefits to include Medical, Dental and Vision
Company match 401k
Eligibility to participate in Employee Stock Purchase Plan
Eligibility to earn commissions/bonus based on company and individual performance
Flexible paid time off (PTO) and sick time
Company
Syneos Health
Syneos Health, the only fully integrated end-to-end clinical and commercial solution organization.
10001+ employees
H1B Sponsorship
Syneos Health has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (35)
2024 (26)
2023 (49)
2022 (63)
2021 (84)
2020 (63)
Funding
Current Stage
Public CompanyTotal Funding
$524.65M2023-09-28Private Equity
2023-05-10Acquired
2021-03-01Post Ipo Secondary· $524.65M
Leadership Team
Costa Panagos
Chief Executive Officer
Michael Bonello
Executive Vice President and Chief Financial Officer
Recent News
2026-01-09
2025-12-01
Company data provided by crunchbase