Senior Software Engineer jobs in United States
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Freenome · 1 day ago

Senior Software Engineer

Freenome is an engineering-forward biotech company that focuses on building reliable and scalable production systems for clinical labs. As a Senior Software Engineer, you will design and maintain secure cloud infrastructure while contributing to critical projects that support scientific computing and clinical lab systems.

BiotechnologyHealth CareHealth DiagnosticsOncologyPersonal Health
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Comp. & Benefits
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H1B Sponsor Likelynote

Responsibilities

Design and implement cloud infrastructure components using Pulumi (Python)
Manage and maintain Kubernetes clusters (AKS, GKE), including node pools, ILBs, and autoscaling configurations
Define observability patterns and implement metrics, dashboards, and alerts in support of production reliability
Contribute to our CI/CD platforms, including build pipeline improvements, deployment strategies, and release automation
Participate in incident response and postmortem analysis for infrastructure-related outages or events
Partner with team members, TPMs, and security stakeholders to deliver infrastructure that meets compliance and reliability requirements
Lead technical implementation of projects or initiatives within your scope
Perform thorough, constructive code reviews and help level up peers through pairing and design discussions
Communicate clearly with cross-functional teams and represent infrastructure in collaborative settings
Model Freenome’s values and principles in your work and interactions
Promote a collaborative, respectful engineering culture with clear communication and inclusive practices
Actively contribute to documentation, playbooks, and engineering standards within the team
Help foster a strong team culture of accountability, learning, and psychological safety
Independently lead the delivery of projects or well-bounded infrastructure systems
Provide mentorship to junior engineers and review designs within your domain
Know when to make architectural tradeoffs with guidance and justify design decisions based on long-term impact
Help evolve our infrastructure practices and participate in team strategy discussions

Qualification

Cloud infrastructureKubernetesPythonTerraformCI/CDNVIDIA DGX systemsTroubleshooting skillsObservability platformsMentorshipCommunication skills

Required

Bachelor's degree in Computer Science, Engineering, or equivalent work experience
Experience with NVIDIA DGX systems and NVIDIA software tech stack
5+ years of experience in software engineering roles (Python preferred), with at least 2 years focused on cloud infrastructure
Production experience with Kubernetes in cloud environments (e.g., AKS, GKE, or EKS)
Proficiency with Terraform, Pulumi, or similar IaC tools
Experience with CI/CD, including deployment automation and release strategies
Familiarity with cloud IAM, networking, and security best practices
Strong troubleshooting and root cause analysis skills in distributed systems
Demonstrated ability to work autonomously and own technical outcomes

Preferred

Experience supporting infrastructure in regulated environments (e.g., healthcare, biotech, financial)
Background in observability platforms such as Prometheus, Grafana, OpenTelemetry)
Exposure to cost optimization, audit logging, or compliance automation in cloud platforms
Experience working with scientists, data engineers, or platform users in cross-functional settings
Interest in mentorship, system design, and infrastructure patterns at scale
Experience with Microsoft Azure

Benefits

Equity
Cash bonuses
Full range of medical, financial, and other benefits

Company

Freenome

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Freenome is a biotechnology company developing blood tests for early cancer detection to improve access to routine screening.

H1B Sponsorship

Freenome has a track record of offering H1B sponsorships. Please note that this does not guarantee sponsorship for this specific role. Below presents additional info for your reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (7)
2024 (11)
2023 (15)
2022 (10)
2021 (7)
2020 (7)

Funding

Current Stage
Late Stage
Total Funding
$1.53B
Key Investors
RocheExact SciencesS32
2025-12-04Acquired
2025-11-17Corporate Round· $75M
2025-08-06Corporate Round· $50M

Leadership Team

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Aaron Elliott
Chief Executive Officer
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Charles Roberts
Co-Founder
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Company data provided by crunchbase