ODDITY LABS · 3 weeks ago
Principal Scientist, Preclinical Drug Discovery and Translational Biology
Cambridge, MA
Full-time
Onsite
Lead/Staff
$120K/yr - $150K/yr
8+ years expODDITY LABS is a cutting-edge biotechnology R&D center focused on innovative product development in the beauty and wellness industries. The Principal Scientist will lead preclinical drug discovery efforts, focusing on skin biology and collaborating across various scientific teams to advance research and development initiatives.
BiotechnologyE-CommerceHealth Care
Responsibilities
Lead and execute preclinical studies with a focus on skin biology, using in vitro and ex vivo models to evaluate efficacy, mechanism of action, and safety
Design, implement, and optimize assays for skin-relevant endpoints, wound healing, pigmentation, lipidomics, inflammation, extracellular matrix organization and barrier function
Develop and validate biomarkers to support target validation and preclinical proof-of-concept
Collaborate with cross-functional partners (chemistry, pharmacology, formulation, and clinical) to align biological strategy with program goals
Manage and guide external CRO relationships for biological assays, skin models, and advanced analytical testing
Contribute to program strategy by interpreting biological data and translating findings into actionable insights for compound advancement
Ensure rigorous experimental design, data analysis, and clear communication of results to internal stakeholders and external collaborators
Maintain awareness of emerging technologies in skin biology and dermatological research, driving innovation in models and methodologies
Advance projects from target validation through preclinical development, ensuring delivery of high-quality data packages that support decision-making and regulatory readiness
Qualification
Required
Ph.D. (or equivalent experience) in Biology, Bioengineering, Pharmacology, or a related life science field
8+ years of industry experience in preclinical drug discovery, translational biology, or related areas, ideally within dermatology, cosmetics, or skin-focused therapeutics
Proven expertise in designing and executing in vitro and ex vivo studies to assess efficacy, safety, and mechanism of action
Hands-on experience with skin-relevant endpoints such as collagen, pigmentation, lipid biology, inflammation, and barrier integrity
Strong knowledge of biomarkers for skin health, aging, and disease, with the ability to integrate biological data into development strategies
Preferred
Previous experience in skin biology and translational research
Benefits
Competitive compensation and benefits package.
This position will consider and sponsor candidates on a visa (OPT, STEM OPT, H1B, TN).
Company
ODDITY LABS
ODDITY LABS is built to become the strongest scientific engine in the global beauty and wellness category.
11-50 employees
H1B Sponsorship
ODDITY LABS has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2024 (3)
Funding
Current Stage
Early StageTotal Funding
$6.5MKey Investors
Intel IgniteMaki.vc
2023-04-27Acquired
2022-11-09Non Equity Assistance
2022-02-17Seed· $6.5M
Leadership Team
A
Avinash Boppana
VP, Partnerships and M&A
Recent News
2025-05-08
2025-05-04
2025-03-01
Company data provided by crunchbase