Senior Scientist / Principal Scientist, Chemistry Lead jobs in United States
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Relay Therapeutics · 1 month ago

Senior Scientist / Principal Scientist, Chemistry Lead

Relay Therapeutics is a clinical-stage precision medicines company transforming the drug discovery process. They are seeking a self-motivated, experienced Medicinal Chemist to develop and execute medicinal chemistry strategies for lead optimization and collaborate with a multi-disciplinary team.

BiotechnologyHealth CareTherapeutics
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Growth Opportunities
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H1B Sponsor Likelynote

Responsibilities

Develop and execute medicinal chemistry strategies on a lead optimization program to deliver a high-quality development candidate in a fast-paced environment
Lead chemists at Relay as well as CRO teams to advance your project
Work closely and collaboratively in a multi-disciplinary team of computational chemists, biophysicists, cell and molecular biologists, pharmacologists, and DMPK specialists

Qualification

Medicinal ChemistryLead OptimizationSynthetic Organic ChemistrySilico Predictive ToolsStructure-Based Drug DesignBiology UnderstandingPharmacology KnowledgeDMPK KnowledgeSafety KnowledgeTeam LeadershipCommunication SkillsCollaborative Work Style

Required

PhD with at least 5 years or MS with at least 8 years of relevant biotech and/or pharmaceutical industry experience in medicinal chemistry, with an emphasis on lead optimization in small molecule drug discovery
You were educated in chemistry with an emphasis on synthetic organic chemistry, synthetic methodology or a related field
You are passionate about working on high impact targets and bringing medicines to patients
You have led or are ready to lead a team and make critical decisions on the SAR direction
You have participated in the delivery of development candidates and your track record of excellence is supported by high impact, peer-reviewed publications and/or patents
You have good understanding of biology, pharmacology, DMPK and safety
You are comfortable enabling your compound design with in silico predictive tools and structure-based drug design
You have strong communication skills, can flex to different work styles, and believe that the best outcomes result from bringing out the creativity of your colleagues
You are committed to building an energetic, collaborative and open company culture and contributing to the company's success

Company

Relay Therapeutics

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Relay therapeutics is a developer of an allosteric drug-discovery platform intended to apply computational techniques to protein motion.

H1B Sponsorship

Relay Therapeutics has a track record of offering H1B sponsorships. Please note that this does not guarantee sponsorship for this specific role. Below presents additional info for your reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (2)
2024 (7)
2023 (2)
2022 (5)
2021 (6)
2020 (1)

Funding

Current Stage
Public Company
Total Funding
$1.4B
Key Investors
Nextech InvestSoftBank Vision FundBiotechnology Value Fund
2024-09-10Post Ipo Equity· $200M
2024-01-08Post Ipo Equity· $30M
2022-09-12Post Ipo Equity· $300M

Leadership Team

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Sanjiv Patel
President and CEO
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Imogen Pryce
Chief Operating Officer, R&D
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Company data provided by crunchbase