Global Therapeutic Research Lead - Immunology jobs in United States
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Takeda · 1 month ago

Global Therapeutic Research Lead - Immunology

Takeda is a forward-looking, world-class R&D organization that unlocks innovation and delivers transformative therapies to patients. The Global Therapeutic Research Lead (GTRL) is responsible for driving Research projects to the clinic, providing mentorship, and leading strategic initiatives within the Gastroenterology and Inflammation Drug Discovery Unit.

BiotechnologyHealth CareManufacturingMedicalPharmaceutical
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H1B Sponsor Likelynote

Responsibilities

Lead and manage one or more ‘Top 10’ drug discovery projects, overseeing the entire drug discovery process from target identification to preclinical development. (Top 10 projects are well validated targets that are focused on strategically aligned modalities with substantial clinical and commercial potential)
Responsible for the articulation and ownership of the project strategy, developed in partnership with internal stakeholders
Contribute to strategy for future portfolio investment, particularly within the Inflammation and Immunology area including advising on which projects should be Top 10 projects
Evaluate and prioritize potential drug candidates based on scientific, medical, and commercial considerations
Represent all core expertise for the project
Partner with Clinical and Translational teams to refine asset strategy
Ensure alignment to the therapeutic area strategy (i.e., Clinical Development)
Understand and align with the commercial team for asset commercial value within the TA
Provide guidance and mentorship to global project team members, stimulating enterprise thinking and fostering their professional growth and development
Mentor future and more junior project leads and elevate drug discovery capability across Research
Collaborate with cross-functional teams and partners (e.g., DMPK, Pharmaceutical Sciences) within and outside Takeda to drive project delivery
Pipeline and enterprise impact through effective partnering with multiple internal and external collaborators
Provide strategic, process, and operational leadership for successful Top 10 Project delivery
Foster a culture of innovation and scientific excellence within the matrixed drug discovery team, promoting collaboration, knowledge sharing, and continuous learning
Become a world leading scientific expert in the projects you lead
Oversee the design and execution of experiments, data analysis, and interpretation to enable decision-making and optimize drug discovery efforts
Stay abreast of the latest advancements in drug discovery, emerging technologies, and industry trends, applying this knowledge to enhance drug discovery strategies
Build and maintain relationships with key stakeholders, including academic institutions, research organizations, and industry partners inclusive of serving on joint external governance committees across the globe
Represent Takeda externally for the Gastroenterology and Inflammation Drug Discovery Unit and play a key role in evaluating external opportunities, serving as an effective ambassador for Takeda’s global business development brand

Qualification

Immunology expertiseDrug discovery leadershipClinical development experienceProject managementBiologics experienceStrategic partnershipsData-driven decision makingCommunication skillsProblem-solving skillsMentorship abilities

Required

PhD degree in a scientific discipline with 15+ years experience, or MS with 21+ years experience, or BS with 23+ years experience
Expected to have at least 10-12 years industry and relevant subject matter expertise within Immunology and Inflammation and at least 10-12 years global management experience, including working effectively with matrix teams
Extensive experience in leading drug discovery teams and managing drug discovery/development projects, preferably in a pharmaceutical or biotechnology setting covering gastroenterology and inflammation
Deep understanding of the drug discovery process, including target identification, hit-to-lead optimization, and preclinical development, anticipating, and removing roadblocks
Proven track record of leading numerous projects, ideally 5+ projects, across discovery from target inception to Candidate Nomination or beyond
Played a major role in 3+ INDs
Has delivered clinical development assets, must include experience with biologics and preferably across multiple modalities
Excellent and inclusive leadership with the ability to inspire and motivate diverse teams towards achieving ambitious goals
Reputation as a proactive, solutions-oriented leader who engages relevant expertise no matter where it resides
Strong business acumen and understanding of the pharmaceutical industry, including regulatory requirements and commercial considerations with relevant knowledge and expertise for specific modalities
Exceptional communication and presentation skills, with the ability to effectively communicate complex scientific concepts to diverse audiences
Proven ability to build and maintain collaborative relationships with internal and external stakeholders across a matrixed organization
Strong problem-solving and decision-making abilities, with a focus on data-driven decision making
Demonstrated success in building and managing strategic partnerships with academic institutions, research organizations, and industry collaborators

Benefits

Medical, dental, vision insurance
401(k) plan and company match
Short-term and long-term disability coverage
Basic life insurance
Tuition reimbursement program
Paid volunteer time off
Company holidays
Well-being benefits
Up to 80 hours of sick time
Up to 120 hours of paid vacation

Company

Takeda

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Takeda is a biopharmaceutical company that researches and develops pharmaceutical drugs.

H1B Sponsorship

Takeda has a track record of offering H1B sponsorships. Please note that this does not guarantee sponsorship for this specific role. Below presents additional info for your reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (45)
2024 (39)
2023 (38)
2022 (34)
2021 (44)
2020 (18)

Funding

Current Stage
Public Company
Total Funding
$2.46B
2025-06-27Post Ipo Debt· $2.4B
2016-09-01Grant· $19.8M
2016-05-08Grant· $38M

Leadership Team

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Christophe Weber
President and CEO
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Schuyler Fairfield
Senior Vice President, Global Head of Supply Chain
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Company data provided by crunchbase