Alnylam Pharmaceuticals · 14 hours ago
Director, Feasibility
Cambridge, MA
Full-time
Hybrid
Director/Executive
10+ years expAlnylam Pharmaceuticals is seeking a Director for their Feasibility Center of Excellence. This role is responsible for leading feasibility strategy and execution across clinical development programs, driving data-informed decisions for protocol optimization, country/site selection, and patient recruitment forecasting.
BiotechnologyHealth CareMedicalPharmaceuticalTherapeutics
Hiring Manager
Adam Lentz, MBA
Responsibilities
Serve as the primary feasibility contact for global studies, supporting timelines, site selection, enrollment projections, and risk mitigation strategies
Deliver high-quality feasibility outputs including data analytics, competitive intelligence, and country-specific insights
Provide subject matter expertise to internal stakeholders and governance forums; escalate feasibility-related risks with actionable recommendations
Lead process improvements and feasibility standards across the organization, contributing to the evolution of the Feasibility CoE vision and strategy
Drive KPI development, performance tracking, and business reporting aligned with operational goals
Mentor and support junior team members; contribute to a culture of innovation and continuous improvement
Champion a patient- and site-centric mindset to ensure inclusive and efficient clinical trial execution
Lead the operational delivery of feasibility assessments across a portfolio of clinical trials, from early planning through site selection
Ensure timely and high-quality feasibility deliverables that inform protocol design, geographic strategy, protocol optimization, and enrollment forecasting
Provide expert input on protocol feasibility, complexity of scoring, site burden, and patient eligibility during the study planning phase
Collaborate with the Sr. Director to set clear goals, support resource planning, team structure, and functional excellence initiatives
Help establish and refine SOPs, work instructions, and best practices for the feasibility function
Monitor key performance indicators (KPIs) for feasibility and enrollment predictability across studies
Drive quality and consistency in feasibility deliverables across therapeutic areas and regions
Partner closely with Clinical Operations, Clinical Science, Commercial, Study Start-Up, etc. to integrate feasibility insights into study planning
Coordinate with external partners (CROs, data vendors, consultants) for feasibility data sourcing and modeling support
Present feasibility findings and recommendations to cross-functional stakeholders and governance bodies
Leverage a wide range of internal and external data sources to inform feasibility assessments, including RWD/RWE, site metrics, epidemiology, and historic trial performance
Promote the use of digital tools, predictive analytics, and AI-driven platforms in feasibility forecasting and modeling
Contribute to the continuous improvement of feasibility templates, dashboards, and methodologies
Qualification
Required
Bachelor's Degree in Life Science or related discipline
Minimum 10 years of experience in clinical research, feasibility, or clinical operations within a pharmaceutical, biotech, or CRO setting
Minimum 3-5 years of feasibility-focused role
Demonstrated ability to lead end-to-end feasibility assessments across multiple studies and/or indications
Deep knowledge of clinical trial design, patient recruitment challenges, and global study execution
Proficiency with feasibility data sources and tools, and data interpretation skills; familiarity with tools like CTMS, Citeline, IQVIA, RWD sources, and feasibility modeling platforms
Excellent leadership, communication, and interpersonal skills
Strategic thinker with strong project management and organizational abilities
Demonstrated ability to influence, collaborate, and lead change across a complex matrixed environment
Willingness to travel up to 10-15%, including international as required
Preferred
Master's degree or higher
Company
Alnylam Pharmaceuticals
Alnylam Pharmaceuticals is a biopharmaceutical company focused on the discovery, development and commercialization.
1001-5000 employees
H1B Sponsorship
Alnylam Pharmaceuticals has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2022 (18)
2021 (19)
2020 (7)
Funding
Current Stage
Public CompanyTotal Funding
$4.55BKey Investors
Blackstone Life SciencesBlackstone CreditRegeneron
2025-09-09Post Ipo Debt· $661.25M
2022-09-12Post Ipo Debt· $900M
2022-03-04IPO
Leadership Team
Yvonne Greenstreet
Chief Executive Officer
Jeff Poulton
Chief Financial Officer
Recent News
2026-01-13
2026-01-13
Company data provided by crunchbase