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Novel Bio · 1 month ago

Research Associate 2, Upstream Process Development

Vancouver, WA

Full-time

Onsite

Entry, Mid Level

1+ years exp

Novel Biotechnology USA, Inc is a life science technology company focused on making genetic medicines more accessible through advanced plasmid DNA biomanufacturing platforms. The Research Associate 2 will play a vital role in the Upstream Process team, executing bioreactor runs, adapting protocols, and collaborating with cross-functional teams to optimize bioprocessing.

BiotechnologyLife Science

Responsibilities

Execute DASGIP bioreactor runs with various microbial hosts (E. coli and proprietary production systems) according to experimental plans

Perform bioreactor setup including media preparation, equipment configuration, and system calibration

Adapt quickly to changing protocols and experimental designs as processes are developed and optimized

Conduct bioreactor takedown, cleaning, and sanitization following SOPs

Perform aseptic sampling during bioreactor runs at specified time points

Process samples for various analytical assays including optical density and plasmid volumetric yield

Maintain accurate and detailed documentation in electronic lab notebooks and batch records

Troubleshoot equipment issues and perform maintenance as needed

Collaborate with cross-functional teams including operations, downstream, and molecular biology groups

Participate in strain evaluation, process optimization studies, and scale-down model development

Maintain laboratory equipment, inventory, and supplies

Cross train on downstream processing activities to gain broad bioprocessing knowledge and to support end-to-end workflows

Qualification

Bioreactor operationsAseptic techniqueMicrobial fermentationDASGIP systemsMolecular biology techniquesAnalytical methodsEntrepreneurial mindsetAttention to detailOrganizational skillsTime management