Volta Labs, Inc. · 3 weeks ago
Molecular Bioengineer
Boston, MA
Full-time
Onsite
Mid, Senior Level
$90K/yr - $110K/yr
4+ years expVolta Labs, Inc. is a Boston based, venture-backed biotech startup that is revolutionizing the future of genomics. They are seeking a Molecular Bioengineer to lead the design, optimization, and productization of NGS workflows on their flagship product Callisto, focusing on creating scalable and reliable molecular workflows.
BiometricsBiotechnologyGenetics
Responsibilities
Design, optimize, and validate core NGS assay steps including enzymatic fragmentation, hybrid capture, size selection, and PCR-free workflows
Translate manual bench-top chemistry into automated protocols compatible with Callisto’s fluidics architecture
Prototype new assay components rapidly to generate early biological data
Define reagent schemas, deck layouts, buffer interactions, hardware tolerances, and consumable requirements
Collaborate with automation and software engineers to ensure seamless execution and reliability on-platform
Troubleshoot biological QC deviations, size distribution discrepancies, and regional coverage biases
Partner with manufacturing to prepare workflows for scale-up and commercial release
Contribute to standardization across Apps and help shape a unified architecture for workflow design
Ramp up on Callisto architecture, assay modules, and workflow constraints
Learn our cross-functional processes—requirements gathering, kit development, and productization flow
Take ownership of selected App workflows and begin designing experiments to refine protocol variants
Fully own molecular workflow development across one or more NGS applications
Independently troubleshoot biology–automation interactions (fragmentation variability, GC bias, dropouts, bead handling issues)
Propose improvements to assay design or platform capabilities and begin implementing mid-sized initiatives
Lead development of new workflow features and next-generation assay architectures
Influence long-term platform design decisions from the perspective of assay scalability and automation constraints
Act as a key contributor to roadmap planning and cross-functional prioritization
Support manufacturing transfer and ensure workflows are robust, reproducible, and ready for scale
Qualification
Required
Master's + 4 years OR PhD + 1 year in Molecular Biology, Bioengineering, Biochemistry, or related field
Strong hands-on experience with molecular workflows; NGS library prep experience strongly preferred
Skilled in experimental design, assay optimization, and troubleshooting complex molecular systems
Familiarity with automated liquid handling or integrated systems
Experience with Illumina, Oxford Nanopore, PacBio, or similar sequencing platforms
Proficient in Python, R or similar languages for data analysis and workflow scripting
Effective communicator and collaborator across R&D, automation, software, and manufacturing teams
Excellent documentation habits; comfortable working in a fast-paced, evolving environment
Preferred
Deep NGS library prep specialization
Experience with hardware integration or microcontrollers
Git/version control familiarity
Exposure to manufacturing transfer or high-scale assay development
Openness to leveraging LLMs for workflow development and analysis acceleration
Benefits
Robust Equity Program , to build future wealth through stock options with high growth potential
Comprehensive Healthcare Coverage , including Medical, Dental, & Vision
HSA with monthly company contribution, & FSA
Sponsored Commuter Benefit Plans
Access to Our 401K Plan , to save for your future
12 Weeks of Paid Parental Leave
Paid Time Off , because we understand the importance of time off for rest and adventure
11 Paid Holidays
Twice Weekly Company Lunches , office snacks, beverages, & treats
Monthly Team Happy Hours and regular team outings!
Company
Volta Labs, Inc.
Volta Labs is a genomics applications company that has developed a cutting-edge digital fluidics platform to maximize performance and scalability of sample preparation in genomics while providing unparalleled consistency.
11-50 employees
H1B Sponsorship
Volta Labs, Inc. has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (5)
2024 (1)
2023 (2)
2021 (3)
Funding
Current Stage
Early StageTotal Funding
$32.68MKey Investors
Maverick Ventures
2024-01-12Series Unknown· $12.68M
2022-03-08Series A· $20M
2019-03-22Seed
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