Zenas BioPharma · 1 month ago
Executive Medical Director, Rheumatology, Global Medical Affairs
Waltham, MA
Full-time
Onsite
Director/Executive
$306K/yr - $383K/yr
10+ years expZenas BioPharma is a clinical-stage global biopharmaceutical company focused on developing transformative therapies for autoimmune diseases. They are seeking an Executive Medical Director, Rheumatology to lead Global Medical Affairs for IgG4-Related Disease and other rheumatologic indications, providing strategic leadership and scientific expertise across various medical activities.
BiopharmaHealth CarePharmaceutical
Responsibilities
Serve as the global medical lead for IgG4-RD and other rheumatologic indications, defining and executing the overall medical strategy in alignment with development, regulatory, and commercial partners
Lead development of the Global Medical Affairs Plan, including scientific narrative, medical objectives, and evidence generation priorities
Ensure medical excellence across the lifecycle, from Phase 3 readout through launch and post-launch activities
Focuses on long-term strategic positioning, cross-portfolio integration, and global alignment across regions
Act as the internal subject matter expert in rheumatology and IgG4-RD, providing scientific guidance to cross-functional teams
Lead interpretation of clinical data, secondary analyses, and emerging scientific insights to inform strategy, publications, and field training
Partner with Clinical Development on protocol design, endpoint refinement, PRO strategy, and data review for trials in rheumatology
Build and maintain strong relationships with global KOLs, investigators, and patient community leaders in rheumatology and immunology
Lead and participate in advisory boards, expert working groups, investigator meetings, and scientific exchanges
Ensure high-quality medical insights are systematically captured and disseminated to inform strategy and decision-making
Oversees global congress strategy and external engagement across all assets
Shape and execute a global communication strategy, including congress planning, publication strategy, symposia, and medical education initiatives
Review and approve scientific content to ensure accuracy, alignment with data, and compliance
Partner with internal teams to build scientific training materials, medical information resources, and launch-ready content
Sets the global evidence-generation strategy across multiple programs including late-phase evidence strategy for IgG4-RD, observational studies, RWE generation, treatment-pattern research, and IIT/IIS programs
Prioritizes which data gaps matter most at a portfolio or therapeutic-area level
Ensures alignment with regulatory, development, and commercial long-term needs
Collaborate with HEOR, RWE, and data science teams to address unmet needs and generate impactful evidence to support access, adoption, and real-world understanding
Support HTA, payer, and access discussions through clear clinical and scientific insights
Partner closely with Regulatory, Clinical Development, Market Access, Commercial, and Legal/Compliance to ensure medical alignment across the business
Provide medical leadership for launch readiness, including Phase 3 data reaction, scientific platform development, field team training, and stakeholder engagement planning
Contribute to scenario planning, competitive intelligence, and risk/benefit discussions
Qualification
Required
MD, DO, PhD, or PharmD with deep scientific understanding of autoimmune diseases
Minimum 10+ years of industry medical affairs and/or clinical development experience
Experience leading global medical strategy and cross-functional initiatives in a biotech or pharmaceutical setting
Proven ability to interpret and communicate complex clinical data and scientific concepts
Track record of high-quality scientific communication (publications, congress participation, advisory boards)
Experience supporting late-phase development, launches, and lifecycle management
Strong understanding of compliance, medical governance, and global regulatory/HTA requirements
Experience in emerging or mid-size biotech environments with a demonstrated ability to build and scale new functions
Excellent communication and interpersonal skills with the ability to build credibility across diverse audiences
Willingness to travel up to 30%, including participation in major rheumatology congresses
Preferred
clinical experience in rheumatology is strongly preferred
experience with rare autoimmune diseases and strong credibility with external experts preferred
Benefits
Annual performance bonus
Equity
Full range of benefits
Other incentive compensation plans
Company
Zenas BioPharma
Zenas BioPharma is a biopharmaceutical company that focuses on developing immune-based therapies for patients.
51-200 employees
H1B Sponsorship
Zenas BioPharma has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (2)
2024 (1)
2021 (2)
Funding
Current Stage
Public CompanyTotal Funding
$513MKey Investors
Royalty PharmaEnavate Sciences
2025-10-08Post Ipo Equity· $120M
2025-09-02Post Ipo Debt· $75M
2024-09-13IPO
Leadership Team
Lonnie Moulder Jr
Chairman
Orlando Oliveira
Chief Commercial Officer
Recent News
2026-01-11
Company data provided by crunchbase