Research Associate – Proteomics/Drug Target Validation jobs in United States
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Monte Rosa Therapeutics · 1 month ago

Research Associate – Proteomics/Drug Target Validation

positionBoston, MA
timeFull-time
remoteOnsite
seniorityEntry, Mid Level
date2+ years exp

Monte Rosa Therapeutics is seeking to recruit a highly motivated research associate to join its Proteomics group in Boston to support hit confirmation and drug target validation. The role focuses on developing and running cell-based assays to validate hits from the company’s proteomics-based screening platform.

BiotechnologyMedicalTherapeutics
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H1B Sponsor Likelynote

Responsibilities

Support research efforts discovering and validating small molecule screening hits through development of cellular assays, including target engagement, ternary complex, and degradation assays
Collaborate with team members to design and execute experiments using routine molecular biology, biochemistry, and cell culture techniques, including working with both immortalized and primary cell lines
Assay optimization identification and fine-tuning of critical assay parameters such as optimal gene expression levels, seeding density, timeframe or co-treatments
Compile and analyze experimental data and communicate research findings at internal meetings
Prepare and manage laboratory stocks of routinely used reagents
Accurately document experimental details through timely maintenance of electronic lab notebook records and the development of standard operating procedures (SOPs) for new protocols

Qualification

Cell culture techniquesCellular biochemistry techniquesAssay developmentData analysisMolecular biologyCommunication skillsCollaborative skillsProblem-solving skillsCritical thinking

Required

BSc and/or MSc in Cell Biology, Biochemistry, or a related field, with at least 2 years of relevant industry or academic research experience
Proficiency in culturing mammalian cells and utilizing sterile techniques (ideally BSL2 standards)
Hands-on experience with a variety of cell culture and cellular biochemistry techniques, including at least several of the following transfection, lentiviral transduction, cell line generation, cell viability assays, SDS-PAGE/Western blot, immunoprecipitation/co-IP, and flow cytometry
Critical and independent thinking, strong analytical and problem-solving skills
Highly collaborative and able to work in a matrix, interactive, and fast-paced drug discovery environment
Excellent oral and written communication skills to work in a collaborative, matrix team

Preferred

Experience with cellular PPI, target engagement, ternary complex or degradation assays

Company

Monte Rosa Therapeutics

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Monte Rosa Therapeutics is a biotechnology company that develops cancer therapeutics that modulate protein degradation pathways.
dateFounded in 2018
location
Basel, Basel-Stadt, CHE
people-size51-200 employees
web-link
https://www.monterosatx.com/

H1B Sponsorship

Monte Rosa Therapeutics has a track record of offering H1B sponsorships. Please note that this does not guarantee sponsorship for this specific role. Below presents additional info for your reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (2)
2024 (1)
2022 (4)
2020 (1)

Funding

Current Stage
Public Company
Total Funding
$648.5M
Key Investors
Avoro Capital AdvisorsAisling Capital
2026-01-08Post Ipo Equity· $300M
2024-05-15Post Ipo Equity· $100M
2023-10-26Post Ipo Equity· $25M

Leadership Team

S
Sharon Townson
Chief Scientific Officer
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Recent News

thefly.com
Monte Rosa Therapeutics 11.125M share Secondary priced at $24.00
2026-01-11
GlobeNewswire
Monte Rosa Therapeutics Announces Pricing of $300 Million Underwritten Public Offering
2026-01-09
BioWorld Financial Watch
Cardio works out for Monte Rosa in NEK7 phase I
2026-01-09
Company data provided by crunchbase