Karius · 3 weeks ago
Senior Bioinformatics Scientist
United States
Full-time
Remote
Mid, Senior Level
$142K/yr - $213K/yr
3+ years expKarius is a life science, venture-backed clinical metagenomics company focused on elevating patient care through microbial insights. The Senior Bioinformatics Scientist will be a key member of the Computational Biomarker Discovery team, responsible for analyzing complex biological data and driving innovations in genomic sequencing and machine learning to advance patient care.
BiotechnologyGeneticsHealth CareInformation TechnologyLife SciencePrecision Medicine
Hiring Manager
Mark Rocha
Responsibilities
Lead data analysis and interpretation of complex biological datasets, including next-generation sequencing (NGS), metagenomics, transcriptomics, fragmentomics, and single-cell analysis
Create or adapt computational tools and algorithms to support biomarker discovery and workflows
Drive bioinformatics aspects of cross-functional research projects in collaboration with scientific and medical leaders, under the guidance of the Director of Computational Biomarker Discovery
Conduct deep exploration of the biological interplay between molecular data and disease conditions, generating insights to advance translational science
Deliver preliminary biological signatures that inform precision medicine applications beyond infectious disease, including autoimmune disorders and oncology
Partner in experimental design by defining analysis plans, selecting appropriate methodologies, and executing computational analyses with a strong grounding in biological rationale
Collaborate closely with scientific, medical, engineering, and commercial teams to set company goals and support the development of new partnerships and products
Ensure high standards of data integrity, quality control, and validation, while maintaining rigorous quality documentation and dissemination of scientific findings
Provide clear visibility into areas of ownership and communicate weekly progress and results to stakeholders
Continue to grow and learn in the necessary biological/scientific domains and technological aspects of the field through novel knowledge acquisition but also staying current with the latest relevant literature
Share enthusiasm for exploring novel applications of Karius’ technology platform to drive innovation and impact
Qualification
Required
Ph.D. in computer science, statistics, mathematics, physics, genetics, bioinformatics, metagenomics, or related fields (preferably with a focus on computational biology or machine learning) with 3+ years of postdoctoral and/or industry experience; OR Master's degree with 5+ years of directly relevant industry experience
Publications demonstrating the use of innovative mathematical or computational models to investigate and interpret biological and biomarker data
Strong background in modern statistics and machine learning, including applications to biomarker discovery
Proven proficiency with high-dimensional, large-scale datasets characterized by low signal-to-noise
Demonstrated excellence in communication and collaboration within cross-functional, multidisciplinary teams
Self-starter with the ability to independently drive results and influence project direction
Evidence of innovation in connecting biological insights to complex mechanisms of microbiome and host–environment interactions
Deep understanding and hands-on experience with bioinformatics tools, methods, and workflows, especially those related to next-generation sequencing (NGS) data analysis
Familiarity with exploratory study and clinical trial designs and analyses, particularly in pharmaceutical or biotechnology applications
Passionate, purpose-driven, and excited about Karius' mission: to conquer infectious diseases through innovations around genomic sequencing and machine learning
Excellence at communication and collaboration within a cross-functional team
Detail oriented with exceptional organizational and time management skills
Self-starting mentality and ability to drive results
Comfortable working in an environment which combines both research aspects as well as development
Ability to work effectively and efficiently in a fast-paced (startup) environment
Company
Karius
Karius delivers genomic insights into infectious diseases, helping clinicians make critical, life-saving treatment decisions.
51-200 employees
H1B Sponsorship
Karius has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2024 (1)
2021 (4)
Funding
Current Stage
Growth StageTotal Funding
$354MKey Investors
SoftBank Vision FundOxford Finance LLCDCVC
2024-05-02Series C· $100M
2020-02-24Series B· $165M
2018-11-30Debt Financing· $25M
Leadership Team
Alexander Ford
Chief Executive Officer
Tim Blauwkamp
Chief Scientific Officer, Co-founder
Recent News
General Catalyst
2026-01-06
2025-05-04
Company data provided by crunchbase