Psomagen · 1 month ago
Senior Scientist, Functional Genomics & Cell Biology
Psomagen, Inc. is a leading provider of next-generation sequencing and multi-omics services headquartered in Rockville, Maryland. They are seeking a highly skilled Senior Scientist to serve as the Technical Lead for their new Functional Genomics facility, focusing on upstream cellular workflows and data analysis to support client projects.
BiopharmaBiotechnologyHealth CareMedical
Responsibilities
Lead the establishment of the new BSL-2 functional genomics suite, including the installation and qualification (IQ/OQ/PQ) of the R3200 platform and ancillary equipment (CO2 incubators, microscopes, centrifuges)
Serve as the primary operator of the R3200, mastering its automated microfluidics and imaging systems
Manage inventory for critical reagents (e.g., hydrogels, antibodies) and cell lines to ensure uninterrupted service operations
Execute project lifecycles focusing on cellular analysis: from cell thawing/culture, drug treatment, and live-cell imaging on the R3200, to on-chip lysis and cDNA elution
Ensure eluted samples meet stringent quality criteria before transferring them to the internal NGS core for library preparation and sequencing
Perform primary quality control on imaging data and preliminary analysis of linked genomic results to validate experimental success before final delivery
Proactively identify and resolve technical issues during experiments; communicate with Cellanome support engineers for complex hardware/software troubleshooting
Travel to Cellanome HQ (or host their FAS) for initial intensive training; continuously update internal protocols based on new feature releases
Support the Business Development Director by providing technical feasibility assessments. Participate in scientific discussions with clients to interpret data and suggest next steps
Author and maintain Standard Operating Procedures (SOPs). Contribute experimental data and technical insights for white papers, application notes, and conference posters
Qualification
Required
Education: Ph.D. in Cell Biology, Molecular Biology, Immunology, or a related field (or M.S. with 5+ years of exceptional relevant experience)
Cell Culture Expertise: Extensive hands-on experience with mammalian cell culture (BSL-2) is essential. Must be proficient in handling sensitive primary cells, transfection/transduction, and clonal expansion
Instrument Proficiency: Experience operating complex automated liquid handling systems, high-content screening (HCS) imagers, or microfluidic single-cell platforms (e.g., 10x Genomics, FACS)
NGS Knowledge: Basic understanding of NGS workflows and sample quality requirements (QC) for successful sequencing, to ensure seamless hand-off to the NGS team
Adaptability: Ability to learn new proprietary software and hardware interfaces quickly. Willingness to travel for initial training
Preferred
Data Analysis Skills: Experience with biological data analysis tools (e.g., ImageJ/Fiji for imaging, basic R/Python for genomics visualization) or software like CellProfiler, FlowJo, or Loupe Browser
Hands-on experience with NGS library preparation (RNA-seq, amplicon-seq)
Experience with CRISPR/Cas9 screening workflows or drug dose-response assays
Previous experience in a CRO or core facility environment, managing multiple projects simultaneously
Bilingual in Korean and English is preferred
Benefits
Competitive salary and benefits package with performance-based bonus plan.
Comprehensive medical, dental, and vision insurance.
401(k) retirement plan with company match.
Career Growth: Opportunity to build and lead a new specialized team as the service volume grows.
Innovation: Direct access to the world's first multi-modal functional genomics platform and the chance to publish/present novel applications.
Company
Psomagen
Psomagen provides genomics services for research, clinical and direct-to-consumer applications.
H1B Sponsorship
Psomagen has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (1)
2024 (2)
2023 (1)
2022 (3)
2021 (7)
2020 (2)
Funding
Current Stage
Growth StageRecent News
2025-04-04
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