Mass General Brigham · 1 month ago
Program Manager - Gene Editing & Therapy
Boston, MA
Full-time
Onsite
Senior Level
$62K/yr - $91K/yr
5+ years expMass General Brigham is a not-for-profit organization that supports patient care, research, teaching, and community service. The Program Manager will manage multiple clinical research studies, oversee Clinical Research Coordinators, and coordinate trial initiation and patient recruitment while ensuring compliance with regulatory standards.
Health CareHome Health CareMedical
Responsibilities
Supervises operations of all study staff
Writes operations manuals
Participates in the formulation of policies and procedures for the study
Prepares Case Report Forms
Coordinates multi-center trials with NIH, FDA and Private foundations
Reports study progress at investigators' meetings
Lead planning, execution, and oversight of preclinical gene editing and gene therapy projects, ensuring alignment with program objectives and timelines
Develop and maintain detailed project plans, including goals, milestones, resource, risk management, and budget tracking
Coordinate with internal teams and external collaborators to design, implement, and analyze preclinical studies, including molecular, cellular, and in vivo experiments
Serve as the primary point of contact for communication between stakeholders, including scientific, operational, and regulatory teams
Ensure preclinical studies comply with GLP, GCP, and relevant regulatory standards
Prepare and review study protocols, reports, and other scientific documentation for internal and external submission
Facilitate decision-making by providing data-driven insights, risk assessments, and project status updates
Monitor technological trends in gene editing/gene therapy and recommend innovative approaches to enhance project outcomes
Support business development efforts, including discussions with potential collaborators and partners
Represent the company at conferences, scientific presentations, and partner meetings as needed
Qualification
Required
Bachelor's Degree Related Field of Study
Research Related Experience 5-7 years
Ability to make independent effective decisions
Strong organizational and communication Skills
Ability to effectively supervise and train Staff
Strong database management and computer skills
Demonstrated analytical skills to problem solve effectively
Must possess strong budget management skills
Ph.D. in Gene Therapy, Molecular Biology, Genetics, Biochemistry, Immunology, or related life sciences; or equivalent experience in industry
Proven experience in Preclinical Project Management, particularly in gene editing (e.g., CRISPR, ARCUS) or gene therapy programs
Demonstrated ability to manage cross-functional teams and multiple projects simultaneously
Strong analytical, problem-solving, and decision-making skills
Excellent verbal and written communication skills, including scientific reporting and stakeholder presentations
Proficient in project management software, Microsoft Office Suite, and data analysis tools
Ability to work independently while fostering collaboration within multidisciplinary teams
Strong organizational ability, attention to detail, and capability to prioritize tasks in a fast-paced, innovation-driven environment
Proactive, self-motivated, and adaptable, with willingness to 'roll up sleeves' and support experimental work as needed
Excellent interpersonal skills, diplomacy, and cultural sensitivity to manage international collaboration
Passion for advancing gene therapy and precision medicine to benefit patients
Preferred
Master's Degree Related Field of Study
Supervisory Experience 1-2 years
Hands-on knowledge of molecular and cellular biology techniques, viral vector handling (AAV, Lentivirus), and in vivo models
Experience with contracting and coordinating work with CROs and external collaborators
Familiarity with regulatory requirements for preclinical studies supporting Investigational New Drug (IND) applications
Benefits
Comprehensive benefits
Career advancement opportunities
Differentials
Premiums and bonuses as applicable
Recognition programs designed to celebrate your contributions and support your professional growth
Company
Mass General Brigham
Mass General Brigham specializes in providing medical treatments and health diagnostics services.
10001+ employees
H1B Sponsorship
Mass General Brigham has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (77)
2024 (61)
2023 (93)
2022 (70)
2021 (80)
2020 (29)
Funding
Current Stage
Late StageLeadership Team
E
Erin Flanigan
SVP, Human Resources, Community, Specialty Hospital Division
O’Neil A. Britton
Chief Integration Officer, Executive Vice President
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