Revolution Medicines · 1 day ago
Executive Director, Clinical Development
San Francisco Bay Area
Full-time
Onsite
Director/Executive
$256K/yr - $320K/yr
13+ years expRevolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies for RAS-addicted cancers. The Executive Director of Clinical Development will be responsible for developing strategic plans and ensuring operational execution of clinical development programs, leading a high-performing team, and managing relationships with stakeholders.
Health CareLife ScienceMedical
Responsibilities
Provide critical insights/contributions and implement comprehensive/execute upon the clinical development plans for Revolution Medicines’ molecules, ensuring alignment with scientific, regulatory, and commercial objectives
Lead, mentor, and manage a high-performing cross-functional team of clinical development professionals, fostering a culture of collaboration, innovation, and excellence
Oversee all aspects of clinical trial design and execution, including site selection, patient recruitment, data management, and regulatory compliance
Establish and maintain strong relationships with clinical investigators, regulatory agencies, and key stakeholders
Gather, analyze and interpret clinical data, providing strategic insights to inform critical decisions and guide program development
Manage clinical development timelines effectively, ensuring efficient resource allocation and achievement of milestones
Stay abreast of the latest scientific advancements and regulatory trends in the field of clinical development
Partner with cross-functional teams, including research, regulatory affairs, commercial, and finance, to ensure seamless program execution and achieve shared goals
Manage multiple direct reports; potentially be a manager of managers
Qualification
Required
MD, PhD or similar advanced biomedical graduate degree with 13+ or more years' experience in pharmaceutical/biotech industry or academic background at the level of Associate Professor or higher
Extensive experience working with the principles and techniques of data analysis, interpretation, and clinical relevance as related to the pharmaceutical/biotech industry
Proven track record of successfully designing and conducting multiple clinical trials as part of a wider clinical development programs from early-stage to late-stage, direct experience with Phase 1 drug development
Experience authoring and clinical development strategy(ies) and bringing forward for governance
Extensive understanding of medical aspects of GCP (Good Clinical Practice), ICH (International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use), FDA, EMA, and other relevant guidelines and regulations
Proven experience to steer an IMP during its clinical development plan through major and varied Health Authority interactions (e.g. FDA, EMA, others). Has led Health Authority interaction(s)
Strong orientation to teamwork. Excellent leadership, communication, and interpersonal skills, with the ability to inspire, motivate and mentor a diverse team
Expertise in building and maintaining strong relationships with internal and external stakeholders
Superb strategic thinking and analytical skills, with the ability to make data-driven decisions in a fast-paced environment. Able to recognize trade-off decisions and can determine priorities and goals
Outstanding written and business presentation skills. Experience publishing results of a clinical trial in a peer-reviewed journal is required
Proven ability to manage budgets and timelines effectively
Passion for innovation and a commitment to developing therapies that make a meaningful difference in patients' lives
Preferred
Experience in ongoing enhancements/development of core and sub-team processes, structures, systems, tools and other resources in the pharmaceutical/biotech industry
Experience creating clinical development strategy(ies) that led to label-enabling outcomes and commercialization
Experience submitting an NDA/BLA/MAA to global health authorities is a significant plus
Has led regulatory and other internal partners/stakeholders in the completion and submission of regulatory documentation. Successfully provided clinical science information and input for regulatory development of label(s) and packaging language, etc
Has led or overseen data generation to address unmet medical needs and identify new or extended Clinical Development studies for the assigned program or other programs
Direct experience with Phase IV drug development
Has proven abilities to present [a] compelling business case and facilitates effective and expeditious decision-making. Has demonstrated the ability to serve as a company spokesperson both internally and externally
Has demonstrated collaborate behaviors on enterprise-level strategic initiatives with a variety of internal and external partners and stakeholders - including clinical investigators/clinicians, scientists and key opinion leaders (KOLs), as well as internal groups, including other groups in development, research, business development, commercial, legal, etc. - resulting in demonstrable outcomes (e.g. new study proposals or new disease indications)
Has demonstrated courage and conviction in past positions and responsibilities. Skilled in conflict resolution
Benefits
Competitive cash compensation
Robust equity awards
Strong benefits
Significant learning and development opportunities
Company
Revolution Medicines
Revolution Medicines is an innovative and dynamic organization of expert biologists, chemists, pharmacologists, clinical scientists.
501-1000 employees
H1B Sponsorship
Revolution Medicines has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (13)
2024 (18)
2023 (15)
2022 (8)
2021 (1)
2020 (2)
Funding
Current Stage
Public CompanyTotal Funding
$2.25BKey Investors
Royalty PharmaBoxer CapitalNextech Invest
2025-06-24Post Ipo Debt· $250M
2024-12-02Post Ipo Equity· $750M
2023-03-02Post Ipo Equity· $323.6M
Leadership Team
Luan Wilfong
Chief Human Resources Officer
Steve Kelsey
President
Recent News
2026-01-08
2026-01-08
2026-01-08
Company data provided by crunchbase