MD Anderson Cancer Center · 1 month ago
Postdoctoral Fellow - Immunology
Houston, TX
Full-time
Onsite
Mid, Senior Level
$64K/yr - $76K/yrMD Anderson Cancer Center is a leading institution in cancer research, seeking a Postdoctoral Fellow in Immunology to advance the understanding of fibroblast behavior in the tumor microenvironment. The role involves designing experiments, utilizing high-throughput single-cell approaches, and applying statistical tests to analyze data, ultimately aiming to redefine targeting strategies for cancer treatment.
Health CareHealth DiagnosticsHospitalMedical
Responsibilities
Take overall responsibility for and drive the proposed project, focusing on fibroblasts and how they both integrate signals and influence other cell types in a variety of disease settings. This entails designing and planning key experiments, troubleshooting, creative problem solving, and taking the initiative to seek out new avenues of inquiry, including collaborations
Gain proficiency in mouse models of cancer, tissue regeneration, and fibrosis. Will gain expertise in fibroblast biology and tumor immunology
Expected to gain expertise in performing statistical tests for rigorous hypothesis testing and data visualization. Scholar will be also expected to develop skills for presenting and effectively communicating research both internally as well as externally at scientific conferences
Apply single-cell and single-nuclei sequencing towards fibroblasts and immune cells in the tumor. This includes the analysis pipeline from raw sequencing data to dataset integration, clustering, pathway analysis, differential gene expression analysis, and other algorithms as the project requires
Gain proficiency in preparing viral vectors for the delivery of transgenes and sgRNA for in vivo CRISPR-based approaches
Gain proficiency in microscopy techniques, including in situ hybridization, multiplexed immunofluorescence, and the analysis of these kinds of data
Take the lead in writing up manuscripts or abstracts on the research with supervision from the PI. May also be asked to assist in the preparation of grant proposals or other literature, such as review articles
Will be expected to take an active role in working with and training lab staff who will be assigned to assist with the project
Qualification
Required
Prior experience with high-dimensional single-cell and/or spatial transcriptomics data analysis and data visualization software is a must
A PhD or equivalent in the fields of Immunology, Cancer Biology, Cell Biology, Systems Biology, Bioinformatics, or Computational Biology is required
Good communication skills with the supervisor and colleagues are a must
Excellent organizational skills of both experimental notes, data, and physical reagents are also a must
Candidate must have demonstrated proficiency in scientific writing through at least one lead-authorship manuscript
Preferred
Experience in flow cytometry, molecular biology, and tissue culture is heavily preferred
As most of the work will focus on preclinical mouse models, a willingness to work with live mice is preferred
Benefits
Medical
Dental
Paid time off
Retirement
Tuition benefits
Educational opportunities
Individual and team recognition
Company
MD Anderson Cancer Center
MD Anderson Cancer Center is a cancer treatment and research institution which gives treatment, and research of all types of cancer.
Founded in 1994
10001+ employees
Funding
Current Stage
Late StageTotal Funding
$16.2MKey Investors
Break Through CancerGastro-Intestinal Research Foundation
2023-05-16Grant· $2.7M
2023-01-24Grant· $3.5M
2022-04-19Grant· $10M
Leadership Team
D
David Tweardy
Professor
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