Principal Engineer, AI Systems jobs in United States
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OneStudyTeam ยท 2 days ago

Principal Engineer, AI Systems

OneStudyTeam is a company that specializes in speeding up clinical trials and improving patient outcomes through its cloud-based platform. The Principal Engineer, AI Systems will act as the senior expert in implementing and integrating AI systems, guiding the deployment of various AI technologies, and collaborating with cross-functional teams to enhance operational efficiency and governance practices.

Clinical TrialsSoftware
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Responsibilities

Lead organization-wide AI adoption and enablement initiatives. Identify opportunities to leverage AI tools to improve efficiency, accuracy, and productivity across business units
Architect, configure, and prototype solutions using LLMs, APIs, and orchestration tools. Develop proof-of-concepts for department-specific AI use cases
Integrate AI capabilities into existing applications, workflows, and cloud environments (e.g., Azure, AWS). Manage connections between enterprise systems and AI platforms through APIs or automation layers
Oversee configuration and operational support of platforms such as OpenAI, Anthropic, Zapier, and Make
Ensure AI implementations adhere to internal policies and external standards, including HIPAA, ISO 27001/27002, and internal data governance frameworks
Implement and promote compliance with frameworks such as NIST AI RMF 1.0 and the EU AI Act. Conduct AI risk assessments and recommend mitigation controls
Partner with department heads and technical teams to evaluate requirements, recommend AI-enabled tools, and support implementation
Serve as a trusted AI advisor to business and technical leaders. Provide internal guidance, training, and documentation on AI tool usage, safety, and best practices
Establish metrics to evaluate AI-driven efficiency gains, user adoption, and business impact
Continuously research, evaluate, and recommend new AI tools, frameworks, and integration strategies aligned with enterprise goals

Qualification

AI deployment frameworksCloud platforms AWSCloud platforms AzurePythonAI/ML certificationsSystems integrationDevOps experienceMLOpsData pipelinesChatbot workflowsCross-functional collaboration

Required

Bachelor's degree in Computer Science, Information Technology, Engineering, or related field (or equivalent practical experience)
Certifications in cloud platforms (AWS, Azure), AI/ML, or information security
10+ years of hands-on experience in software engineering, systems integration, or DevOps
3+ years of experience implementing and managing AI or automation tools in enterprise environments
Deep understanding of AI deployment frameworks
Experience integrating AI systems with enterprise applications, APIs, and data infrastructure
Strong Python and scripting skills for automation and AI orchestration
Proven ability to translate business problems into AI-enabled technical solutions
Familiarity with HIPAA, ISO 27001/27002, and secure software development practices
Working knowledge of NIST AI RMF 1.0 and EU AI Act risk categorization principles
Demonstrated ability to work cross-functionally and communicate technical solutions to non-technical audiences
Experience leading AI governance, security, or compliance initiatives in regulated industries
Experience with MLOps, data pipelines, or enterprise automation platforms such as Zapier and Make
Prior experience developing or managing chatbot workflows, prompt engineering, or AI knowledge bases
Familiarity with productivity-enhancing tools such as Microsoft Copilot, Slack AI, Salesforce AI, or similar enterprise AI integrations

Company

OneStudyTeam

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OneStudyTeam is a cloud-based software company that work to ensure therapeutic development moves at the speed of science. It is a sub-organization of Reify Health.

Funding

Current Stage
Growth Stage

Leadership Team

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Ralph Passarella
CEO, Co-Founder
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Carson L R.
Lead Talent Acquisition Partner, Technology
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