Principal Applied Scientist jobs in United States
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Microsoft · 9 hours ago

Principal Applied Scientist

Microsoft is a leading technology company focused on empowering individuals and organizations. They are seeking a Principal Applied Scientist to lead the development of the Copilot Chat Assistant, which aims to enhance the advertising experience by utilizing advanced AI technologies and methodologies.

Agentic AIApplication Performance ManagementArtificial Intelligence (AI)Business DevelopmentDevOpsInformation ServicesInformation TechnologyManagement Information SystemsNetwork SecuritySoftware
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Growth Opportunities
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H1B Sponsor Likelynote

Responsibilities

Own the science roadmap for Copilot Chat Assistant - from ideation to reliable, safe production launches
Design multi‑agent reasoning systems that blend LLM orchestration, tool use, and state management for long‑running tasks
Build robust retrieval pipelines (RAG + vector stores) for precise, grounded answers across advertiser and campaign domains
Advance prompt/program design (planning, decomposition, self‑reflection, evaluation) to boost accuracy, latency, and cost efficiency
Ship real features with engineering partners: telemetry, online evaluations/A‑B tests, guardrails, red‑teaming, and quality bars
Mentor and multiply: guide applied scientists and engineers, set best practices, and raise the bar for scientific rigor
Measure impact: define success metrics, instrument experiments, and iterate quickly based on data and customer feedback

Qualification

Large Language ModelsAgentic FrameworksVector DatabasesRetrieval Augmented GenerationStatisticsPredictive AnalyticsResearchMentoringCollaborationProblem Solving

Required

Bachelor's Degree in Statistics, Econometrics, Computer Science, Electrical or Computer Engineering, or related field AND 6+ years related experience (e.g., statistics, predictive analytics, research)
OR Master's Degree in Statistics, Econometrics, Computer Science, Electrical or Computer Engineering, or related field AND 4+ years related experience (e.g., statistics, predictive analytics, research)
OR Doctorate in Statistics, Econometrics, Computer Science, Electrical or Computer Engineering, or related field AND 3+ years related experience (e.g., statistics, predictive analytics, research)
OR equivalent experience

Preferred

Master's Degree in Statistics, Econometrics, Computer Science, Electrical or Computer Engineering, or related field AND 9+ years related experience (e.g., statistics, predictive analytics, research)
OR Doctorate in Statistics, Econometrics, Computer Science, Electrical or Computer Engineering, or related field AND 6+ years related experience (e.g., statistics, predictive analytics, research)
OR equivalent experience
5+ years experience developing and deploying live production systems, as part of a product team
7+ years experience developing and deploying products or systems at multiple points in the product cycle from ideation to shipping
Experience using LLMs, agentic frameworks, RAG, vector databases to build complex production systems

Company

Microsoft

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Microsoft is a software corporation that develops, manufactures, licenses, supports, and sells a range of software products and services.

H1B Sponsorship

Microsoft has a track record of offering H1B sponsorships. Please note that this does not guarantee sponsorship for this specific role. Below presents additional info for your reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (9192)
2024 (9343)
2023 (7677)
2022 (11403)
2021 (7210)
2020 (7852)

Funding

Current Stage
Public Company
Total Funding
$1M
Key Investors
Technology Venture Investors
2022-12-09Post Ipo Equity
1986-03-13IPO
1981-09-01Series Unknown· $1M

Leadership Team

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Satya Nadella
Chairman and CEO
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Vukani Mngxati
Chief Executive Officer - Microsft South Africa
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Company data provided by crunchbase