Alnylam Pharmaceuticals · 15 hours ago
Scientist, Analytical Sciences
Cambridge, MA
Full-time
Onsite
Mid, Senior Level
$114K/yr - $154K/yr
5+ years expAlnylam Pharmaceuticals is a leader in RNAi therapeutics, and they are seeking a Scientist in Analytical Sciences to support clinical-stage programs. The successful candidate will be responsible for developing and qualifying analytical assays, authoring regulatory documents, and providing analytical support for investigations related to quality and manufacturing.
BiotechnologyHealth CareMedicalPharmaceuticalTherapeutics
Responsibilities
Develop, qualify, and troubleshoot chromatographic (GC, HPLC/UPLC) and LCMS based methods for the identification, characterization, and impurity profiling of oligonucleotides, siRNAs, and their formulations, as well as raw material related analytical methods and other methods as needed
Understand and apply advanced scientific principles, theories, concepts, practices and standards to process and analytical development
Provide analytical support for investigations leading by quality, manufacturing, supply chain
Perform testing of late development siRNA candidates and their formulations for their characterization
Author method development and qualification reports and SOPs for test methods. Evaluate suitability of new methods and oversee method qualification and validation in the external contract testing labs
Author and review analytical sections in regulatory submission documents
Apply strong technical knowledge of organic and analytical chemistry to support laboratory investigations (deviations/OOS/OOT), as needed
May serve as a primary contact person for cross-departmental needs or projects and be accountable for key deliverables
Contribute to the development and/or improvement of technical capabilities as well as initiatives to improve department efficiency
Qualification
Required
Master's degree with minimum 5 years related industry experience or Bachelor's degree with minimum 8 years related industry experience respectively, with demonstrated chromatographic separation, method development / qualification and structure elucidation expertise
Experience with HPLC/UPLC and LCMS-based analytical method development desired
Strong interpersonal skills, communication, and collaboration
Preferred
PhD in Chemistry, Biochemistry or related disciplines with relevant industry experience preferred
Familiarity with instrument troubleshooting and software including Empower, MassHunter, and UNIFI preferred
Knowledge of GxP requirements and application of statistical methods in the analytical laboratory is a plus
Hands-on experience with oligonucleotides is a plus
Benefits
Medical, dental, and vision coverage
Life and disability insurance
Lifestyle reimbursement program
Flexible spending and health savings accounts
401(k) with a generous company match
Paid time off
Wellness days
Holidays
Two company-wide recharge breaks
Generous family resources and leave
Company
Alnylam Pharmaceuticals
Alnylam Pharmaceuticals is a biopharmaceutical company focused on the discovery, development and commercialization.
1001-5000 employees
H1B Sponsorship
Alnylam Pharmaceuticals has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2022 (18)
2021 (19)
2020 (7)
Funding
Current Stage
Public CompanyTotal Funding
$4.55BKey Investors
Blackstone Life SciencesBlackstone CreditRegeneron
2025-09-09Post Ipo Debt· $661.25M
2022-09-12Post Ipo Debt· $900M
2022-03-04IPO
Leadership Team
Yvonne Greenstreet
Chief Executive Officer
Jeff Poulton
Chief Financial Officer
Recent News
2025-12-22
2025-12-20
Company data provided by crunchbase