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MESO SCALE DIAGNOSTICS, LLC. · 3 weeks ago

Senior Scientist, Computational Protein Engineering

Gaithersburg, MD

Full-time

Onsite

Mid, Senior Level

$117K/yr - $178K/yr

2+ years exp

Meso Scale Diagnostics, LLC. is a company focused on developing innovative diagnostic solutions. The Senior Scientist in Computational Protein Engineering will plan and develop an in-silico platform for antibody and protein engineering, collaborating with other scientists and leading technical teams to implement computational pipelines.

Innovation ManagementManufacturingTest and Measurement

No H1B

Responsibilities

Independently designs and develop an in-silico platform for antibody and other protein engineering in collaboration with other scientists in the group and across the company

Develops computational pipelines for protein structure determination using structural and/or sequence-based methods and/or artificial intelligence methods (e.g. Rosetta, AlphaFold)

Develops computational pipelines for protein docking and antibody epitope mapping

Independently combines data from different sources and analyze these or incorporate these into multidimensional optimization of protein interactions

Leads a technical team to implement computational pipelines in protein design, engineering, or prediction

Critically evaluates experimental data and incorporate this knowledge into design

Provides input to the management team to identify, develop, and execute departmental initiatives and strategies

Leads technical team(s) to accomplish project goals and manages/coordinates work of other team members

Presents findings/analyses and any associated issues/solutions to peer groups and managers; make recommendations for project advancement

Leads cross-functional initiatives with other business units on projects/products or associated deliverables

Establishes and monitors direct report performance and development goals, assigns accountabilities, sets objectives, establishes priorities, and provides continuous coaching and recognition on performance

Stays current technological developments in area of expertise, expands knowledge through independent learning

Maintains organized, detailed and clear project records for self and direct reports

Understands, follows and enforces laboratory safety precautions to ensure compliance with company safety policies

Qualification

Protein modelingComputational pipelinesPhD in relevant fieldArtificial intelligenceMachine learningAnalytical skillsLeadership skillsCommunication skillsOrganizational skillsTeam collaboration

Required

PhD in structural bioinformatics, molecular biology, bioengineering, biophysics, computational biology, or related field with 2 years of relevant experience

Expertise with protein and antibody modeling, including antigen-antibody interactions

Publications in the form of high-profile papers/patents within protein prediction or de novo protein design, including antibody or enzyme engineering

Proven record of remaining current, learning new techniques/research in areas of computational biochemistry

Superior scientific fundamentals and analytical background

Ability to work independently and in teams, and to collaborate with external parties

Excellent communication skills and the ability to working in a highly dynamic and collaborative environment

Expert problem solving skills and demonstrated ability to organize and move project tasks forward in an orderly and structured fashion

Strong analytical skills with the demonstrated ability to gather and evaluate complex data and information and develop a recommendation and plan of action

Excellent organizational, planning, and time management skills required, with the ability to manage multiple and often changing priorities and issues of varying complexity while meeting time-sensitive deadlines and deliverables

Strong leadership skills with demonstrated knowledge and understanding of staff management practices and processes. Ability to establish accountabilities and expectations and manage performance to achieve results

Demonstrated propensity to be creative, collaborative, proactive, and self-motivated in the execution and completion of assigned tasks

Exceptional communication (written and verbal) skills regardless of the format (e.g., documents, public speaking situations, presentations, etc.)

Project-level understanding and attention to detail with demonstrated commitment to excellence and performance

Proven proficiency with Microsoft Office (i.e., Word, Excel, PowerPoint, Outlook)

Preferred

Experience with artificial intelligence and/or machine learning methods is desirable

Benefits

Medical, dental, and vision coverage, along with prescription benefits

401(k) plan with company matching

Flexible spending accounts

Company-paid short- and long-term disability insurance

Group life and accidental death and dismemberment insurance

Paid vacation

Paid sick leave

Paid holidays

Paid parental leave

Employee assistance program

Fitness club membership contribution

Pet insurance

Identity theft protection

Home and auto insurance discounts

Optional supplemental life insurance

Company

MESO SCALE DIAGNOSTICS, LLC.

Glassdoor3.2

Founded in 1995, Meso Scale Discovery (MSD) is a global leader in the development, manufacture, and commercialization of innovative assays and instruments for the measurement of molecules in biological samples.

Founded in 1995

Rockville, Maryland, USA

1001-5000 employees