MapLight Therapeutics, Inc. · 6 hours ago
Scientist, Non-clinical Toxicology
Burlington, MA
Full-time
Hybrid
Mid, Senior Level
$127K/yr - $144K/yr
3+ years expMapLight Therapeutics is a clinical stage biotech company that focuses on drug discovery for central nervous system disorders. The role involves designing, executing, and interpreting non-clinical safety studies to support neurology drug discovery and development programs.
BiopharmaBiotechnologyLife ScienceMedical
Responsibilities
Collaborate with program team leads and subject matter experts (e.g., discovery, bioanalysis, pharmacokinetics, CMC) to design safety pharmacology and toxicology studies, aligning with company objectives and regulatory standards
Serve as the primary sponsor representative for CROs, handling all aspects of study outsourcing, including requesting quotes, negotiating contracts, and managing study timelines
Oversee the design, execution, and data interpretation of nonclinical safety studies conducted at CROs, ensuring robust and high-quality data generation
Review study reports and SEND datasets to ensure quality, timeliness, and readiness for regulatory submissions
Effectively communicate study findings project leads and senior management, addressing and resolving any study-related issues promptly
Contribute to the preparation, review, and/or QC of nonclinical sections in regulatory submission documents (e.g., IBs, INDs, CTAs, NDAs, PIPs, Scientific Advice, annual reports, briefing documents) as needed
Participate in issue-resolution teams, providing scientific guidance to address toxicology-related challenges and drive effective problem-solving
Qualification
Required
PhD with 3+ years, MS with a minimum of 5+ years, or BS with a minimum of 8 years of hands-on experience as a study director in toxicology within the pharmaceutical or biotechnology industry or at CROs (additional experience monitoring studies on-site at CROs is helpful)
Proven track record of successfully directing and/or monitoring toxicology studies across various modalities and in various species (rodent, dog, nhp)
Advanced knowledge of toxicology in support of drug development
In-depth understanding of GLP regulations and regulatory guidance for nonclinical evaluations
Demonstrated enthusiasm for scientific research and a commitment to maintaining high-quality standards in toxicology study operations
Strong critical thinking, analysis, and leadership skills
Self-motivated to meet performance objectives and to prioritize job-related tasks
Ability to adapt to dynamic project needs and manage studies across different time zones
Excellent interpersonal, communication, and negotiation skills, with a collaborative mindset
Willingness to travel on business to CROs as needed
Preferred
Board Certification in toxicology (DABT Certification) or working towards board certification preferred but not required
Benefits
Annual bonus opportunity
Medical
Dental
Vision
Life and AD&D
Short term and long term disability
401(K) plan with match
Stock options
Flexible non-accrual paid time off
Parental leave
Company
MapLight Therapeutics, Inc.
Maplight is a biopharmaceutical company discovering and developing novel therapeutics for patients with disorders of the central nervous system (CNS).
51-200 employees
H1B Sponsorship
MapLight Therapeutics, Inc. has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (1)
2024 (1)
Funding
Current Stage
Public CompanyTotal Funding
$640.6MKey Investors
Michael J. Fox Foundation
2025-10-27IPO
2025-07-28Series D· $372.5M
2023-10-30Series C· $225M
Leadership Team
Vishwas Setia
Chief Financial Officer
Recent News
Pharma Letter
2025-12-18
2025-12-16
Company data provided by crunchbase